Treating Pythiosis with Antibacterial Drugs Targeting Protein Synthesis: An Overview.

J Fungi (Basel)

Department of Pharmacology, Basic Health Sciences Institute, Federal University of Rio Grande do Sul, 2600 Ramiro Barcelos Street, Porto Alegre 90035-003, RS, Brazil.

Published: March 2024

This review article explores the effectiveness of antibacterial drugs that inhibit protein synthesis in treating pythiosis, a difficult-to-treat infection caused by . The article highlights the susceptibility of to antibacterial drugs, such as macrolides, oxazolidinones, and tetracyclines. We examine various studies, including in vitro tests, experimental infection models, and clinical case reports. Based on our synthesis of these findings, we highlight the potential of these drugs in managing pythiosis, primarily when combined with surgical interventions. The review emphasizes the need for personalized treatment strategies and further research to establish standardized testing protocols and optimize therapeutic approaches.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11051233PMC
http://dx.doi.org/10.3390/jof10040234DOI Listing

Publication Analysis

Top Keywords

antibacterial drugs
12
treating pythiosis
8
protein synthesis
8
pythiosis antibacterial
4
drugs
4
drugs targeting
4
targeting protein
4
synthesis overview
4
overview review
4
review article
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!