Norovirus is a major cause of acute gastroenteritis; GII.4 is the predominant strain in humans. Recently, 2 new GII.4 variants, Hong Kong 2019 and San Francisco 2017, were reported. Characterization using GII.4 monoclonal antibodies and serum demonstrated different antigenic profiles for the new variants compared with historical variants.
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| http://dx.doi.org/10.3201/eid3005.231694 | DOI Listing |
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Molecular epidemiology and temporal evolution of norovirus associated with acute gastroenteritis in Amazonas state, Brazil.
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Background: Globally, Norovirus (NoV) is considered the most common cause of diarrheal episodes across all age groups. Despite its wide genetic diversity, the GII.4 strain is the most predominant and has been associated with epidemics worldwide.
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PLoS One
February 2017
Department of Clinical Infection, Microbiology & Immunology, Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom.
Noroviruses are endemic in the human population, and are recognised as a leading cause of acute gastroenteritis worldwide. Although they are a highly diverse group of viruses, genogroup-II genotype-4 (GII-4) noroviruses are the most frequently identified strains worldwide. The predominance of GII-4 norovirus strains is driven by the periodic emergence of antigenic variants capable of evading herd protection.
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J Clin Virol
November 2014
Department of Microbiology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. Electronic address:
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High serum levels of norovirus genotype-specific blocking antibodies correlate with protection from infection in children.
J Infect Dis
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Vaccine Research Center, University of Tampere Medical School.
Article Synopsis
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PLoS One
October 2014
Virus Reference Department, Microbiology Services, Public Health England, London, United Kingdom.
Article Synopsis
- - Norovirus is the leading cause of acute gastrointestinal disease and is especially prevalent in confined settings, with infections peaking in England from December to March each year.
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