Creating artificial synapses that can interact with biological neural systems is critical for developing advanced intelligent systems. However, there are still many difficulties, including device morphology and fluid selection. Based on Micro-Electro-Mechanical System technologies, we utilized two immiscible electrolytes to form a liquid/liquid interface at the tip of a funnel nanochannel, effectively enabling a wafer-level fabrication, interactions between multiple information carriers, and electron-to-chemical signal transitions. The distinctive ionic transport properties successfully achieved a hysteresis in ionic transport, resulting in adjustable multistage conductance gradient and synaptic functions. Notably, the device is similar to biological systems in terms of structure and signal carriers, especially for the low operating voltage (200 mV), which matches the biological neural potential (∼110 mV). This work lays the foundation for realizing the function of iontronics neuromorphic computing at ultralow operating voltages and in-memory computing, which can break the limits of information barriers for brain-machine interfaces.
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http://dx.doi.org/10.1021/acs.nanolett.3c05079 | DOI Listing |
Nano Lett
May 2024
School of Integrated Circuits, Peking University, Beijing 100871, People's Republic of China.
Creating artificial synapses that can interact with biological neural systems is critical for developing advanced intelligent systems. However, there are still many difficulties, including device morphology and fluid selection. Based on Micro-Electro-Mechanical System technologies, we utilized two immiscible electrolytes to form a liquid/liquid interface at the tip of a funnel nanochannel, effectively enabling a wafer-level fabrication, interactions between multiple information carriers, and electron-to-chemical signal transitions.
View Article and Find Full Text PDFPhys Chem Chem Phys
August 2022
Microfluidics and Microscale Transport Laboratory, Department of Mechanical Engineering, Indian Institute of Technology Guwahati, Assam 781039, India.
Salinity energy generation (SEG) studies have only been done under isothermal conditions at ambient temperature. The production of salinity energy can be improved under non-isothermal conditions, albeit preserving the energy efficiency. In the current study, the effects of gradients of temperature and concentration on the salinity energy generation process were examined simultaneously.
View Article and Find Full Text PDFNanoscale
May 2022
Institute of Quantitative Biology, Shanghai Institute for Advanced Study, College of Life Sciences, and Department of Physics, Zhejiang University, Hangzhou 310027, China.
High-fidelity DNA sequencing using solid-state nanopores remains a big challenge, partly due to difficulties related to efficient molecular capture and subsequent control of the dwell time. To help address these issues, here we propose a sequencing platform consisting of stacked two-dimensional materials with tailored structures containing a funnel-shaped step defect and a nanopore drilled inside the nanochannel. Our all-atom molecular dynamics (MD) simulations showed that, assisted by the step defect, single-stranded DNA (ssDNA) can be transported to the nanopore in a deterministic way by pulsed transversal electric fields.
View Article and Find Full Text PDFNanomaterials (Basel)
March 2022
Department of Industrial Technology Education, National Kaohsiung Normal University, Kaohsiung 824, Taiwan.
Ion current rectification (ICR) phenomena in asymmetric nanofluidic structures, such as conical-shaped nanopores and funnel-shaped nanochannels, have been widely investigated in recent decades. To date, the effect of asymmetric nanofluidic structures on electrokinetic power generation driven by the streaming current/potential has not been explored. Accordingly, this study employed a numerical model based on the Poisson equation, Nernst-Planck equation, and Navier-Stokes equation to investigate the electrokinetic energy conversion (EKEC) in a conical nanopore while considering hydrodynamic slippage.
View Article and Find Full Text PDFNano Lett
May 2021
Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China.
Chloride transport participates in a great variety of physiological activities, such as regulating electrical excitability and maintaining acid-base equilibrium. However, the high flux is the prerequisite to ensure the realization of the above functions. Actually, the high flux of ion transport is significant, not only for living things but also for practical applications.
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