AI Article Synopsis

  • In Eastern culture, women with darker skin face beauty standards that favor a fair complexion, leading to distress and a demand for whitening cosmetics.
  • A study was conducted to evaluate the safety and efficacy of a compound formula called TEST, which includes ingredients like astaxanthin and nicotinamide, for skin whitening.
  • Results showed that TEST was safe, improved skin tone significantly, and reduced the melanin index after treatment, suggesting it can be used in skin-whitening products.

Article Abstract

Background: In Eastern culture, a fair complexion is the standard of beauty, leading to appearance-related distress among women with darker skin or facial pigmentation. Women seek whitening cosmetics to enhance their skin tone or correct their pigmentation, but their safety and effectiveness are paramount factors to consider. In this study, we evaluated the safety and whitening effects of a compound formula denoted as TEST comprising astaxanthin, nicotinamide, arbutin, and tranexamic acid.

Methods: Primary skin irritation and skin-whitening efficacy were examined. Three qualified melanization areas were treated with TEST, 7% ascorbic acid, or a blank. Skin color, the individual type angle (ITA°), and the melanin index (MI) were compared among treatment areas.

Results: TEST did not induce a skin response and exhibited a significantly higher ITA° than the blank, while no significant difference was observed with that of 7% ascorbic acid. Furthermore, the MI of TEST was significantly reduced posttreatment.

Conclusions: TEST could be integrated into spot-fading and skin-whitening cosmeceuticals or functional cosmetics.

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Source
http://dx.doi.org/10.1111/jocd.16332DOI Listing

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