AI Article Synopsis
- - The study investigated the effectiveness and safety of a modified thread carpal tunnel release procedure (mTCTR) using Smartwire-01 in patients with carpal tunnel syndrome (CTS).
- - Patients showed significant improvement in symptom severity and functional status at 4 weeks post-procedure, with benefits persisting through 12 weeks; no adverse effects were reported.
- - Changes in nerve function, specifically latency and velocity of the median nerve, indicated improvement after the procedure, while the median nerve cross-sectional area remained unchanged.
Article Abstract
Purpose: This study aimed to investigate the effectiveness and safety of modified thread carpal tunnel release (mTCTR) using Smartwire-01 in patients with carpal tunnel syndrome (CTS).
Materials And Methods: Patients with CTS who required CTR were enrolled. Symptom severity and functional status were assessed using the Boston Carpal Tunnel Syndrome Questionnaire-Symptom Severity Scale (BCTQ-SSS) and Functional Status Scale (BCTQ-FSS), and pain was assessed using a numerical rating scale (NRS) at 4, 8, and 12 weeks after mTCTR. The scores were compared with the pre-procedural scores. The electrophysiologic study and median nerve cross-sectional area (CSA) measurements at the wrist before and 12 weeks after mTCTR were compared.
Results: A total of 11 patients were included. No adverse effects were reported throughout the study period. The NRS, BCTQ-SSS, and BCTQ-FSS scores significantly improved at 4 weeks after mTCTR, and this improvement persisted throughout the follow-up period (NRS and BCTQ-SSS, P < 0.001; BCTQ-FSS, P = 0.012). After 12 weeks, the latency and velocity of the median sensory nerve action potential significantly improved, compared with those before mTCTR (latency, 5.4 ± 1.3 to 4.7 ± 1.1 ms, P = 0.01; velocity 27.8 ± 6.8 to 31.8 ± 7.4 m/s, P = 0.019). No significant change was observed in the median nerve CSA before and after mTCTR.
Conclusion: mTCTR using Smartwire-01 is a safe and effective procedure and a possible alternative to surgery.
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| http://dx.doi.org/10.1055/a-2280-3507 | DOI Listing |
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