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SARS-CoV-2 live virus culture and sample freeze-thaw stability. | LitMetric

SARS-CoV-2 live virus culture and sample freeze-thaw stability.

Diagn Microbiol Infect Dis

Department of Pathology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA.

Published: July 2024

The effect of freeze-thaw on SARS-CoV-2 viral viability is not well established. We isolated virus from 31 split clinical samples cultured fresh or after a 7- or 17/18-day freeze. We found that freeze-thaw did not significantly affect viral culture isolation. Therefore, frozen samples may be used to assess SARS-CoV-2 infectiousness.

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Source
http://dx.doi.org/10.1016/j.diagmicrobio.2024.116282DOI Listing

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