Targets can distort competition in favor of incumbent firms.
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PSMA-PET/CT Findings in Patients With High-Risk Biochemically Recurrent Prostate Cancer With No Metastatic Disease by Conventional Imaging.
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Ahmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles.
Importance: The phase 3 randomized EMBARK trial evaluated enzalutamide with or without leuprolide in high-risk nonmetastatic hormone-sensitive prostate cancer. Eligibility relied on conventional imaging, which underdetects metastatic disease compared with prostate-specific membrane antigen-positron emission tomography (PSMA-PET).
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Introduction: Previous studies have examined the predictive accuracy of plasma amyloid beta (Aβ) biomarkers in clinical cohorts. However, their accuracy for predicting amyloid-positive patients in community-based cohorts is unclear. This study aimed to determine the predictive accuracy of Aβ precursor protein 669-711/Aβ1-42, Aβ1-40/1-42 and their composite biomarkers for brain amyloid deposition or the clinical progression in community-dwelling older adults with mild cognitive impairment (MCI).
View Article and Find Full Text PDFActive phytoextraction of toluene shifts the microbiome and enhances degradation capacity in hybrid poplar.
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School of Environmental Sciences, University of Guelph, 50 Stone Rd E, Guelph, ON, N1H 2W1, Canada. Electronic address:
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China 19T'' Metallurgical Group Corporation Limited, 610039, Chengdu, China.
As one of the primary precast components in prefabricated construction, composite slabs have increasingly attracted interest for their costs as well as carbon footprint in production and installation stages. Conventional methods for separating composite slabs can lead to a building project necessitating multiple specifications of composite slabs. Due to the requirement to customize molds for different modulus of composite slabs, the production process experiences a substantial rise in energy consumption and resource waste.
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