Objective: To report the corneal clarity outcome following lamellar keratectomy of arcus lipoides corneae secondary to canine hypothyroidism and report a unique retinal manifestation of systemic disease.
Animal Studied: Four-year-old spayed female Sheepdog-Poodle canine.
Procedure: Lamellar keratectomy OD.
Results: Bilateral severe arcus lipoides corneae was noted in the initial presentation. Bilateral, symmetric, and multifocal bullous retinal detachments were observed at subsequent visits. Biochemical testing revealed hyperlipidemia presumed to be associated with primary acquired thyroiditis. Corneal clarity and visual behaviors were significantly improved following unilateral lamellar keratectomy with no evidence of recurrence within the year following surgery. Bilateral retinal detachments and hyperlipidemia resolved months after initiation of thyroxine supplementation. Corneal lipidosis in the untreated eye remained static.
Conclusions: Lamellar keratectomy is a viable surgical option for the treatment of arcus lipoides corneae. Hypothyroidism should be considered a differential diagnosis for spontaneous, bilateral, multifocal, and serous retinal detachments.
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http://dx.doi.org/10.1111/vop.13223 | DOI Listing |
Vestn Oftalmol
December 2024
Pirogov Russian National Research Medical University, Moscow, Russia.
This review analyzes the primary etiological factors of diffuse lamellar keratitis following various laser corneal refractive surgery techniques. The use of advanced diagnostic methods such as optical coherence tomography, confocal microscopy, and immunohistochemical methods has allowed for the identification of the main pathogenetic mechanisms underlying this condition, which will help improve the prevention, as well as assist with the development of optimal treatment strategies for this complication.
View Article and Find Full Text PDFSmall
December 2024
National Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu, Sichuan, 610065, China.
Collagen as the main structural component of the cornea exhibits unique and highly organized fibril lamellae, which contribute to the maintenance of corneal structure and transparency. Nevertheless, collagen assembly in vitro to create ideal artificial corneal substitutes with human cornea comparable thickness and optics is still limited. Here, glycerol as a regulator can reconcile collagen thickness, transparency, and permeability, a conflicting goal by current keratoprosthesis strategies.
View Article and Find Full Text PDFJ Cataract Refract Surg
December 2024
Rio de Janeiro, Brazil.
A 23-year-old woman was referred for low visual acuity in the left eye after a corneal ulcer associated with contact lens use 2 years previously. The patient had a history of contact lens use, reported use of antibiotic eye drops with improvement of infection, and subsequent scarring. There were no comorbidities.
View Article and Find Full Text PDFJ Epidemiol Glob Health
December 2024
Ophthalmology Department, King Saud University, Riyadh, Saudi Arabia.
Background: Corneal pathologies are among the most common reversible sight-threatening diseases globally. As such, corneal tissue transplantation (keratoplasty) techniques are evolving over time depending on the prevalence of different pathologies in each geographical area. We aim to provide a baseline information on the common keratoplasty procedures performed in our area in relation to prevalent corneal pathologies and to analyze common corneal surgical practice trends in our area.
View Article and Find Full Text PDFVet Ophthalmol
October 2024
Department of Ophthalmology, Puchol Veterinary Hospital, Madrid, Spain.
Objective: To describe a case of presumed band keratopathy in a young cat with no known history of corneal disease who was not receiving topical phosphate-based steroids.
Animal Studied: A 10-month-old domestic shorthair cat was evaluated for severe ocular discomfort that did not improve despite the initiation of topical antibiotic treatment.
Methods: A complete ophthalmic examination and ancillary tests such as biomicroscopy and corneal cytology were performed at the time of presentation.
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