AI Article Synopsis
- The study compared a new anesthesia machine's automatic control system with manual control by anesthesiologists in 76 patients undergoing gynecological surgeries.
- Results showed that while both methods had similar anesthetic depth and consumption, the automatic system achieved the desired anesthetic target faster and with much fewer adjustments required.
- The conclusion indicates that the automatic control mode is more efficient for managing anesthesia during surgeries compared to the manual approach.
Article Abstract
Purpose: New-generation anesthesia machines administer inhalation anesthetics and automatically control the fresh gas flow (FGF) rate. This study compared the administration of minimal flow anesthesia (MFA) using the automatically controlled anesthesia (ACA) module of the Mindray A9 (Shenzhen, China) anesthesia machine versus manual control by an anesthesiologist.
Methods: We randomly divided 76 patients undergoing gynecological surgery into an ACA group (Group ACA) and a manually controlled anesthesia group (Group MCA). In Group MCA, induction was performed with a mixture of 40-60% O and air with a 4 L/min FGF until the minimum alveolar concentration (MAC) reached 1. Next, MFA was initiated with 0.5 L/min FGF. The target fraction of inspired oxygen (FiO) value was 35-40%. In Group ACA, the MAC was defined as 1, and the FiO was adjusted to 35%. Depth of anesthesia, anesthetic agent (AA) consumption, time to achieve target end-tidal AA concentration, awakening times, and number of ventilator adjustments were analyzed.
Results: The two groups showed no statistically significant differences in depth of anesthesia or AA consumption (Group ACA: 19.1 ± 4.9 ml; Group MCA: 17.2 ± 4.5; p-value = 0.076). The ACA mode achieved the MAC target of 1 significantly faster (Group ACA: 218 ± 51 s; Group MCA: 314 ± 169 s). The number of vaporizer adjustments was 15 in the ACA group and 217 in the MCA group.
Conclusion: The ACA mode was more advantageous than the MCA mode, reaching target AA concentrations faster and requiring fewer adjustments to achieve a constant depth of anesthesia.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s10877-024-01163-0 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The ACA Medicaid expansions and abortion rates among young adults.
Eur J Health Econ
January 2025
Arkansas Tech University, Arkansas, USA.
This paper examines whether the expansion of Medicaid under the Affordable Care Act (ACA), which increases access to contraceptives to low-income childless women and allows them more autonomy to determine the timing of their pregnancies and births, is associated with lower abortion rates during the period 2008-2017. Using state-level data from the Guttmacher Institute and employing a difference-in-differences method, we find that Medicaid expansion is associated with a meaningful reduction in the abortion rate among women ages 18-24, presumably through increased use of contraceptives among low-income young adults. Our estimates imply that Medicaid expansion is associated with a relative decrease in the abortion rate among this age group, approximately 1-2 per 1000 women.
View Article and Find Full Text PDFLack of association of the PLD4 SNP rs2841277 with systemic sclerosis in a European American population.
Sci Rep
December 2024
Internal Medicine/Rheumatology, University of Texas Health Science Center at Houston, Houston, 77030, USA.
This study aimed to examine whether a reported SSc-associated SNP rs2841277 in the PLD4 gene identified in an Asian population was also associated with SSc in European American (EA). The EA cohort consisting of 1005 SSc patients and 961 healthy controls was examined in this study. TaqMan genotyping assays were performed to examine the SNP.
View Article and Find Full Text PDFExploring Immune-Mediated Brain Function Abnormalities in Systemic Lupus Erythematosus: Neuroimaging Evidence of the Impact of Anti-Ribosomal P Protein Antibodies.
Acad Radiol
December 2024
Department of Radiology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China (S.L., S.C., J.X., L.T., X.L.). Electronic address:
Rationale And Objectives: Neuropsychiatric systemic lupus erythematosus (NPSLE) is one of the most severe complications of systemic lupus erythematosus (SLE), and its early biomarkers and immune mechanisms remain unclear. This study utilizes Resting-State functional magnetic resonance imaging (rs-fMRI) to explore early neuroimaging biomarkers and potential immune mechanisms of brain injury in SLE, with a particular focus on anti-ribosomal P protein antibody (ARPA).
Materials And Methods: A total of 47 SLE patients and 33 healthy controls (HCs) underwent rs-fMRI.
Thermoresponsive gel embedding extracellular vesicles from adipose stromal cells improves the healing of colonic anastomoses following irradiation in rats.
Commun Biol
December 2024
Laboratoire de Recherche en Imagerie du Vivant, PARCC, INSERM U970, Université Paris Cité, Paris, France.
Anastomotic leak occurrence is a severe complication after colorectal surgery. Considering the difficulty of treating these leaks and their impact on patient care, there is a strong need for an efficient prevention strategy. We evaluated a combination of extracellular vesicles (EVs) from rat adipose-derived stromal cells with a thermoresponsive gel, Pluronic® F127 (PF-127) to prevent anastomotic leaks.
View Article and Find Full Text PDFFactors affecting women's access to primary care in the United States since the Affordable Care Act: A mixed-methods systematic review.
PLoS One
December 2024
Division of Health Research, Faculty of Health and Medicine, Lancaster University, Lancaster, Lancashire, United Kingdom.
Background: In the United States, the Affordable Care Act (ACA) expanded public and private health coverage, increased health insurance affordability, reduced healthcare costs, and improved healthcare quality for many. Despite ACA provisions, lack of insurance and other factors continue to affect working-age women's access to primary care services.
Methods: We conducted a mixed-method systematic review to identify factors that affect women's access to primary care services since the ACA.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!