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Prevalence of infection in Chinese military personnel: A cross-sectional, multicenter-based study.
World J Gastroenterol
January 2025
Department of Gastroenterology and Hepatology, The First Medical Center, Chinese People's Liberation Army General Hospital, Beijing 100853, China.
Background: () infection is a prevalent disease encountered in military internal medicine and recognized as the main cause of dyspepsia, gastritis, and peptic ulcer, which are common diseases in military personnel. Current guidelines in China state all patients with evidence of active infection with are offered treatment. However, the prevalence of infection and its regional distribution in the military population remain unclear, which hinders effective prevention and treatment strategies.
View Article and Find Full Text PDFChange in sleep, gastrointestinal symptoms, and mood states at high altitude (4500m) for 6 months.
Sleep Breath
January 2025
Department of Neurology, 940th Hospital of Chinese People's Liberation Army Joint Logistic Support Force, Lanzhou, 730050, China.
Purpose: This study aimed to investigate the alterations in sleep quality and sleep patterns among military personnel at altitudes ranging from 1500 to 4500 m, as well as the associated factors influencing their sleep.
Methods: This study employed a longitudinal prospective survey conducted over a period of six months, from November 2023 to June 2024. A total of 90 soldiers were recruited for participation.
Evaluation of the therapeutic effects of nebulized inhalation of hydrogen-rich water on primary blast lung injury in C57BL/6 mice.
Surgery
January 2025
Senior Department of Burns & Plastic Surgery, Institute of Burn in the Fourth Medical Centre, Chinese PLA General Hospital, Beijing, China. Electronic address:
Background: Primary blast lung injury is a common and severe consequence of explosion events, characterized by immediate and delayed effects such as apnea and rapid shallow breathing. The overpressure generated by blasts leads to alveolar and capillary damage, resulting in ventilation-perfusion mismatch and increased intrapulmonary shunting. This reduces the effective gas exchange area, causing hypoxemia and hypercapnia.
View Article and Find Full Text PDFMetallothionein rescues doxorubicin cardiomyopathy via mitigation of cuproptosis.
Life Sci
January 2025
Department of Cardiology, Cardiac Arrhythmia Center, Affiliated Hospital of Nantong University, Nantong 226001, China. Electronic address:
Doxorubicin (DOX), a chemotherapeutic agent utilized in the management of cancer, provokes cardiotoxicity although effective remedy is lacking. Given that DOX provokes oxidative stress and cell death in cardiomyocytes, this study evaluated the possible involvement of cuproptosis, a newly identified form of cell death, in DOX-instigated cardiac remodeling and contractile dysfunction, alongside the impact of the heavy metal scavenger metallothionein (MT) on DOX cardiomyopathy. Cardiac-specific MT transgenic and wild-type (WT) mice were treated with DOX (5 mg/kg/wk.
View Article and Find Full Text PDFUsing Implementation Science to Assess Barriers to Agreement on Sedation Goal Setting and Assessment.
Pediatr Crit Care Med
January 2025
Perioperative & Critical Care-Center for Outcomes Research and Evaluation (PC-CORE), Boston Children's Hospital, Boston, MA.
Objectives: Sedation assessment and goal setting using a validated assessment tool are key components of the ICU Liberation bundle. Appropriate integration of these bundle elements into daily practice remains challenging. Understanding barriers is an important step toward implementation of these best practice bundle elements.
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