Two new alkaloids from L. and their anti-inflammatory and anticholinesterase activities.

Two new alkaloids identified as 2-(((S,Z)-1-(1H-azirin-1-yl)-5-methylhex-1-en-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol and (S,Z)-1-(1H-azirin-1-yl)-5-methylhex-1-en-3-ol, named olerazirin A (), olerazirin B (), together with five known alkaloids, identified as cyclo (L-Val-L-Ala) (), cyclo-(glycyl-L-leucine) (), cyclo-(Gly-Phe) (), cyclo (Ser-Phe) (), (3S,6S)-3-[(1R)-1-hydroxyethyl]-6-(phenyl-methyl)-2,5-piperazinedione () were obtained from L. using a range of chromatographic techniques, 1D and 2D NMR, and high-resolution electrospray ionisation time-of-flight mass spectroscopic methods, in which the compounds - were isolated from for the first time. In addition, the results showed that the compounds and have anti-inflammatory activities and compounds - and - exhibit the anticholinesterase activities.