Paratesticular myxoid liposarcoma is an exceedingly rare malignancy originating from the spermatic cord or paratesticular tissues. We report a unique case of a 75-year-old male patient who presented with a painless scrotal swelling that had been growing for four years. Imaging investigations, including ultrasonography (USG) and contrast-enhanced computerized tomography (CECT), revealed characteristics consistent with paratesticular myxoid liposarcoma. The orchidectomy specimen confirmed a grade 2 right paratesticular myxoid liposarcoma. Despite its rarity, clinicians must consider this tumor in the differential diagnosis of painless scrotal swellings. Accurate diagnosis and comprehensive management, encompassing surgical resection with wide margins and potential adjuvant therapies, are pivotal. This case underlines the importance of collaborative research and long-term follow-up in understanding and managing paratesticular myxoid liposarcomas.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11040278 | PMC |
| http://dx.doi.org/10.7759/cureus.56859 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Myxoid Pleomorphic Liposarcoma of the Spermatic Cord: A Rare Entity at a Rare Site.
Cureus
July 2024
Department of Radiology, Sri Ramaswamy Memorial (SRM) Institute of Science and Technology, Chengalpattu, IND.
Article Synopsis
- Myxoid pleomorphic liposarcoma (MPLPS) is a rare form of liposarcoma recently added to medical literature, typically arising from adipose tissue in extremities and retroperitoneum.
- Paratesticular liposarcomas are particularly uncommon, and MPLPS often occurs in the mediastinum, but can also affect limbs and regions like the head and neck.
- The case study describes a 50-year-old male with a swelling in the right inguinal area, diagnosed with MPLPS after an orchidectomy and subsequent histopathological analysis, marking the first reported instance of this condition affecting the spermatic cord.
CD34/S100 protein-positive, NTRK1-rearranged infantile fibrosarcoma-like tumors in genitourinary system: two cases expanding the clinicopathologic spectrum and illustrating the diagnostic dilemma.
Virchows Arch
September 2024
Department of Pathology, Fudan University Shanghai Cancer Center, #270 Dong-an Road, Shanghai, 200072, China.
Infantile fibrosarcoma (IFS) is malignant fibroblastic tumor of infants characterized genetically by ETV6::NTRK3 fusion. Tumors that show morphology indistinguishable from IFS but harbor alternative genetic alterations are uncommon, which have been designated as IFS-like tumors. We report two cases of IFS-like tumors harboring an NTRK1 rearrangement and arsing from genitourinary system.
View Article and Find Full Text PDFMyxoid Inflammatory Myofibroblastic Sarcoma: Clinicopathologic Analysis of 25 Cases of a Distinctive Sarcoma With Deceptively Bland Morphology and Aggressive Clinical Behavior.
Am J Surg Pathol
August 2024
Department of Pathology, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA.
The number of recognized sarcoma types harboring targetable molecular alterations continues to increase. Here we present 25 examples of a distinctive myofibroblastic tumor, provisionally termed "myxoid inflammatory myofibroblastic sarcoma," which might be related to inflammatory myofibroblastic tumor, and which occurred in 13 males (52%) and 12 females at a median age of 37 years (range: 7 to 79 years). Primary tumor sites were peritoneum (18 patients; 72%), paratesticular (2; 8%), chest wall (1), upper extremity (1), esophagus (1), retroperitoneum (1), and uterus (1).
View Article and Find Full Text PDFA case report of giant paratesticular myxoid liposarcoma.
Urol Case Rep
May 2024
Urology B Department, Avicenne Hospital, University Hospital Center IBN SINA, University Mohammed V, Rabat, Morocco.
Liposarcomas are an uncommon occurrence in the paratesticular region that makes about 20 % of all sarcomas. The clinical appearance is an inguinal lump, which can resemble a hydrocele or hernia. There would be no conventional treatment accessible because it is such a rare disease.
View Article and Find Full Text PDFGiant Paratesticular Myxoid Liposarcoma: A Case Report of a Rare Entity.
Cureus
March 2024
Department of Radiology, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Tamil Nadu, Chennai, IND.
Paratesticular myxoid liposarcoma is an exceedingly rare malignancy originating from the spermatic cord or paratesticular tissues. We report a unique case of a 75-year-old male patient who presented with a painless scrotal swelling that had been growing for four years. Imaging investigations, including ultrasonography (USG) and contrast-enhanced computerized tomography (CECT), revealed characteristics consistent with paratesticular myxoid liposarcoma.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!