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http://dx.doi.org/10.1016/j.jcin.2024.02.024DOI Listing

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•Percutaneous repair of severely regurgitant atrioventricular valves in the setting of a Fontan circulation utilizing Tri-Clip, even in the setting of an atrioventricular septal defect, is feasible.•Percutaneous options hold promise as a low-risk repair strategy in this highly complex population, which generally has a high surgical risk.

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Transcatheter Repair of Tricuspid Valve Regurgitation: A Systematic Review.

J Clin Med

October 2024

Structural Heart & Valve Center, Houston Heart, HCA Houston Healthcare Medical Center, Tilman J. Fertitta Family College of Medicine, The University of Houston, Houston, TX 77004, USA.

Clinically significant severe tricuspid regurgitation (TR) is a common untreated pathology associated with increased mortality. Even though surgical valve replacement has been the mainstay option, transcatheter intervention is a novel and potentially effective tool. To the best of our knowledge, this is the first systematic review that assessed and compared clinical and echocardiographic outcomes of coaptation and annuloplasty devices in patients with clinically significant TR.

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Article Synopsis
  • Novel transcatheter therapies for tricuspid regurgitation (TR) show promise, but their suitability for the general TR patient population is still uncertain.
  • In a study involving 178 patients with moderate symptomatic TR, only 10.7% qualified for investigative therapies, while many received off-label clipping, surgery, or medical treatment due to factors like unsuitable anatomy or existing health issues.
  • Although the investigative group experienced significant improvement in TR severity after one year compared to the medical treatment group, their outcomes were similar to off-label clipping but not as favorable as surgery, highlighting the need for broader access to effective therapies for TR patients.
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Case report: Transcatheter edge-to-edge repair after prior surgical tricuspid annuloplasty.

Front Cardiovasc Med

October 2022

Division of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, University Düsseldorf, Dūsseldorf, Germany.

Residual and recurrent tricuspid regurgitation may occur frequently after surgical tricuspid valve repair. However, reoperation for tricuspid regurgitation is rare, although many patients are again highly symptomatic. Tricuspid transcatheter edge-to-edge repair (TEER) is a promising therapy for severe tricuspid regurgitation.

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