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Two new triterpenoid saponins and two new goodyerosides isolated from the whole plant of . | LitMetric

Two new triterpenoid saponins and two new goodyerosides isolated from the whole plant of .

Nat Prod Res

Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, Yanbian University College of Pharmacy, Yanji, P.R. China.

Published: April 2024

Two new triterpenoid saponins (oleanolic acid 2-hydroxyl-3---D-glucuronopyranoside-6--buthyl ester () and oleanolic acid 2-hydroxyl-3--[-D-glucuronopyranosyl-6'--methylester]-28---D-glucopyranoside ()) and two new goodyerosides (4-methylenefuran-2(5)-one (6'--vanilloyl)--D-glucopyranoside (), 3-hydroxy-2(5)-furanone, 4-(6'--vanilloyl)--D-glucopyranoside ()), together with seven known compounds (-) were isolated from the whole plant of L. The chemical structures of the compounds were determined by spectroscopic analysis (1D and 2D NMR) and HR-ESI-MS. Compounds , and showed significant cytotoxicity towards A549, SK-Hep1 and HeLa cells, with IC values ranging from 1.68 ± 0.09 to 6.87 ± 0.13 μM.

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Source
http://dx.doi.org/10.1080/14786419.2024.2345755DOI Listing

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