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The Impact of Mammographic, Radiologist, and Patient Factors on the Likelihood of Probably Benign (BI-RADS 3) Assessment at Diagnostic Mammography. | LitMetric

AI Article Synopsis

  • The study aimed to assess how different factors (mammographic, radiologist, and patient-related) influence the classification of BI-RADS 3 during diagnostic mammograms for patients referred from screening.
  • A total of 12,080 diagnostic mammograms were analyzed, with 16.6% resulting in a BI-RADS 3 classification; asymmetry and calcifications were significantly linked to this assessment, whereas distortion, dense breasts, prior exams, and older age were associated with lower likelihood.
  • The findings concluded that while asymmetry and calcifications increase the chances of a BI-RADS 3 assessment, the overall likelihood of malignancy in BI-RADS 3 cases was low at 1.6%, and factors related

Article Abstract

Objective: To evaluate the association of mammographic, radiologist, and patient factors on BI-RADS 3 assessment at diagnostic mammography in patients recalled from screening mammography.

Methods: This Institutional Review Board-approved retrospective study of consecutive unique diagnostic mammography examinations in asymptomatic patients recalled from screening mammography March 5, 2014, to December 31, 2019, was conducted in a single large United States health care institution. Mammographic features (mass, calcification, distortion, asymmetry), breast density, prior examination, and BI-RADS assessment were extracted from reports by natural language processing. Patient age, race, and ethnicity were extracted from the electronic health record. Radiologist years in practice, recall rate, and number of interpreted diagnostic mammograms were calculated. A mixed effect logistic regression model evaluated factors associated with likelihood of BI-RADS 3 compared with other BI-RADS assessments.

Results: A total of 12 080 diagnostic mammography examinations were performed during the study period, yielding 2010 (16.6%) BI-RADS 3 and 10 070 (83.4%) other BI-RADS assessments. Asymmetry (odds ratio [OR] = 6.49, P <.001) and calcification (OR = 5.59, P <.001) were associated with increased likelihood of BI-RADS 3 assessment; distortion (OR = 0.20, P <.001), dense breast parenchyma (OR = 0.82, P <.001), prior examination (OR = 0.63, P = .01), and increasing patient age (OR = 0.99, P <.001) were associated with decreased likelihood. Mass, patient race or ethnicity, and radiologist factors were not significantly associated with BI-RADS 3 assessment. Malignancy rate for BI-RADS 3 lesions was 1.6%.

Conclusion: Asymmetry and calcifications had an increased likelihood of BI-RADS 3 assessment at diagnostic evaluation with low likelihood of malignancy, while radiologist features had no association.

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Source
http://dx.doi.org/10.1093/jbi/wbae014DOI Listing

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