AI Article Synopsis

  • * Medical examinations revealed severe hypotension and issues with esophageal motility, including lower esophageal stricture and hypercontraction, while high-resolution manometry indicated premature contractions and reduced peristalsis.
  • * The man's symptoms related to food stagnation and vomiting improved after endoscopic balloon dilation, highlighting that distal esophageal spasm (DES) can be a complication in MSA patients.

Article Abstract

A 74-year-old man developed orthostatic syncope, a feeling of food stuck in his chest, and postprandial vomiting 3 years before presentation. Examination revealed severe orthostatic hypotension and cerebellar ataxia, and he was diagnosed with multiple system atrophy (MSA) with predominant cerebellar ataxia. Videofluoroscopic examination of swallowing showed lower oesophageal stricture and barium stagnation within the oesophagus. Oesophagogastroduodenoscopy revealed hypercontraction of the lower oesophagus, and high-resolution oesophageal manometry showed premature contractions of the lower oesophagus and decreased oesophageal peristalsis. The median integrated relaxation pressure in the lower oesophageal sphincter was normal, and achalasia was therefore excluded. Based on the Chicago classification version 4.0, his oesophageal dysmotility was classified as distal oesophageal spasm (DES). The stuck feeling in his chest and vomiting improved following endoscopic balloon dilation. This case suggests that DES can cause oesophageal food stagnation and postprandial vomiting in patients with MSA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11035085PMC
http://dx.doi.org/10.1016/j.ensci.2024.100500DOI Listing

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