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Commentary to the letter: "Atrophy of posterior spinal muscles in aging women with painful idiopathic lumbar or thoracolumbar scoliosis. Case-control study analyzing camptocormia".
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Service de Médecine Physique et de Réadaptation, Clermont-Ferrand, INRAE, Université Clermont Auvergne, France.
Immunotherapy in advanced non-small cell lung cancer: What to do for the 'Invisible' patients after IPSOS trial results?
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Division of Thoracic Oncology, European Institute of Oncology, IRCCS, Milan, Italy.
Background: Immune checkpoint inhibitors (ICIs) are currently included in the standard of care of the first-line treatment of advanced/metastatic non-small cell lung cancer (NSCLC). However, a relevant group of clinically unfit patients, including poor Performance Status, Elderly, and those with relevant comorbidities, are not represented in most pivotal clinical trials.
Methods: An expert panel meeting commentary was virtually held to point out the key issues in treating such 'invisible' patients and to review the available evidence.
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D.L. Gumucio is professor emerita, Department of Cell and Developmental Biology and Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan.
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