Undernourished Household Contacts Are at Increased Risk of Tuberculosis (TB) Disease, but not TB Infection-a Multicenter Prospective Cohort Analysis.

Pranay Sinha Komala Ezhumalai Xinyi Du Chinnaiyan Ponnuraja Madolyn Rose Dauphinais Nikhil Gupte Sonali Sarkar Amita Gupta Sanjay Gaikwad Balamugesh Thangakunam Mandar Paradkar Devasahayam J Christopher Vidya Mave Vijay Viswanathan Jerrold J Ellner Hardy Kornfeld C R Horsburgh Chandrasekaran Padmapriyadarsini Akshay Gupte

Clin Infect Dis

Department of Global Health, Boston University School of Public Health, Boston, Massachusetts, USA.

Published: July 2024

- Undernutrition is the top risk factor for tuberculosis (TB) worldwide and specifically in India.
- A study in India found that undernutrition increases the risk of developing TB disease but not the risk of getting TB infection among people living with TB patients.
- The research involved multiple centers and tracked household contacts of individuals with TB to evaluate these associations.

Undernutrition is the leading risk factor for tuberculosis (TB) globally and in India. This multicenter prospective cohort analysis from India suggests that undernutrition is associated with increased risk of TB disease but not TB infection among household contacts of persons with TB.

Download full-text PDF	Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11259213	PMC
http://dx.doi.org/10.1093/cid/ciae149	DOI Listing

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