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Two undescribed coumarins from . | LitMetric

Two undescribed coumarins from .

Nat Prod Res

Department of Pharmacology, Chongqing Medical University, Chongqing, China.

Published: April 2024

Two previously undescribed coumarins ( and ) were isolated from the root of which have been used to cure inflammatory diseases over thousands of years by Chinese. The structures of new findings were confirmed by comprehensive analyses of spectral evidences in HRESIMS, 1D and 2D NMR combined with chemical calculations. Compounds and exhibited potential anti-inflammatory properties by reducing the mRNA expression levels of , and in lipopolysaccharide (LPS)-induced RAW264.7 macrophages at a concentration of 15 μM.

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Source
http://dx.doi.org/10.1080/14786419.2024.2343921DOI Listing

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