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ZnFe Layered Double Hydroxide Nanosheets Loaded with Cu Single-Atom Nanozymes with Multi-Enzyme-Like Catalytic Activities as an Effective Treatment for Bacterial Keratitis.
Adv Sci (Weinh)
January 2025
College of Chemistry and Pharmacy, Northwest A&F University, Yangling, Shaanxi, 712100, P. R. China.
Bacterial keratitis (BK) is a type of corneal inflammation resulting from bacterial infection in the eye. Although nanozymes have been explored as promising materials in corneal wound healing, currently available nanozymes lack sufficient catalytic activity and the ability to penetrate bacterial biofilms, limiting their efficacy against the treatment of BK. To remedy this, ZnFe layered double hydroxide (ZnFe-LDH) nanosheets are loaded with Cu single-atom nanozymes (Cu-SAzymes) and aminated dextran (Dex-NH), resulting in the formation of the nanozyme DT-ZnFe-LDH@Cu, which possesses peroxidase (POD)-, oxidase (OXD)-, and catalase (CAT)-like catalytic activities.
View Article and Find Full Text PDFShort-Term Outcomes of Dual Versus Single Antiplatelet Therapy Following Popliteal and Infrapopliteal Endovascular Therapy: Data From Dutch Chronic Lower Limb-Threatening Ischemia Registry (THRILLER).
J Endovasc Ther
January 2025
Department of Vascular Surgery, Northwest Hospital Group, Alkmaar, The Netherlands.
Objective: There is a lack of consensus regarding the optimal antithrombotic therapy (ATT) after popliteal and infrapopliteal (PIP) endovascular therapy (EVT). Currently, dual antiplatelet therapy (DAPT) for 3 months and single antiplatelet therapy (SAPT) are the most prescribed regimens in the Netherlands. Thus far, no randomized comparison has been performed on the optimal ATT approach.
View Article and Find Full Text PDFHerbal Medicines as Complementary Therapy for Managing Complications in COVID-19 Patients with Diabetes Mellitus.
Diabetes Metab Syndr Obes
January 2025
Center of Excellence for Pharmaceutical Care Innovation, Universitas Padjadjaran, Sumedang, Indonesia.
Diabetes mellitus (DM) is recognized and classified as a group of conditions marked by persistent high blood glucose levels. It is also an inflammatory condition that may influence concurrent disease states, including Coronavirus Disease 2019 (COVID-19). Currently, no effective drug has been found to treat COVID-19, especially in DM patients.
View Article and Find Full Text PDFMapping the priority conservation areas for three endangered Cupressaceae plants under climate change in China.
Front Plant Sci
January 2025
China Eco-city Academy Co., Ltd., Tianjin, China.
The establishment of conservation areas is an important strategy for endangered species conservation. In this study, we investigated the distributions of suitable habitat areas for three level 1 endangered Cupressaceae plants (, , and ) in China and used the Marxan model to delineate the priority conservation areas for each species. The results showed that had the broadest suitable growing area under the current climate in China and is followed by , with an area of 91 × 10 km, and had the smallest suitable habitat areas at only 7 × 10 km.
View Article and Find Full Text PDFWildland fire entrainment: The missing link between wildland fire and its environment.
PNAS Nexus
January 2025
Southern Research Station, US Forest Service, 320 Green Street, Athens, GA 30602, USA.
Wildfires are growing in destructive power, and accurately predicting the spread and intensity of wildland fire is essential for managing ecological and societal impacts. No current operational models used for fire behavior prediction resolve critical fire-atmospheric coupling or nonlocal influences of the fire environment, rendering them inadequate in accounting for the range of wildland fire behavior scenarios under increasingly novel fuel and climate conditions. Here, we present a new perspective on a dominant fire-atmospheric feedback mechanism, which we term wildland fire entrainment (WFE).
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