AI Article Synopsis
- Flea-borne typhus (FBT), or murine typhus, is a zoonotic infection that occurs worldwide, but is relatively rare in the U.S., with endemics noted in places like Los Angeles County.
- FBT usually presents as a mild fever but can lead to serious complications like hemophagocytic lymphohistiocytosis (HLH) in some cases.
- The report discusses a specific case where the patient was treated with doxycycline for FBT and successfully recovered from HLH, along with a review of similar documented cases.
Article Abstract
Flea-borne typhus (FBT), also known as murine typhus, is a zoonotic infection caused by with world-wide distribution. In the United States, the infection is uncommon but remains endemic in some areas, including Los Angeles County. It typically manifests as a benign acute febrile illness but can be complicated in a minority of cases. Associated hemophagocytic lymphohistiocytosis (HLH) has been described in a limited number of cases. Here, we present a case of a patient with FBT complicated by HLH treated empirically with doxycycline with subsequent resolution of HLH. Also included is a review of the literature of other published cases.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11031783 | PMC |
| http://dx.doi.org/10.1016/j.idcr.2024.e01955 | DOI Listing |
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- A case involving an abattoir worker presented symptoms like fever, jaundice, and renal failure, eventually diagnosed with both infections through various lab tests.
- This case highlights the importance of timely and accurate diagnosis for effective treatment of these rare coinfections to prevent severe health complications.
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