Permanent Pacemaker-Mediated Exertional Hypoxemia in a Patient With Ebstein Anomaly.

JACC Case Rep

Section of Cardiology, Department of Internal Medicine, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.

Published: April 2024

AI Article Synopsis

  • Ebstein anomaly patients often experience increased interatrial communications and abnormal blood flow, primarily due to tricuspid regurgitation or high right atrial pressure.
  • In a unique case, a permanent pacemaker lead inadvertently maintained an open patent foramen ovale, causing right-to-left shunting of blood.
  • This situation resulted in exertional hypoxemia and is noted as the first report of its kind in existing literature.

Article Abstract

Patients with Ebstein anomaly are known to have a higher incidence of interatrial communications and shunting of blood and its components through, mainly due to either streaming of tricuspid regurgitation or due to elevated right atrial pressure. Here we describe a case where permanent pacemaker lead kept a patent foramen ovale open leading to right-to-left shunting of blood and exertional hypoxemia. This is the first such case report in the published literature.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11031675PMC
http://dx.doi.org/10.1016/j.jaccas.2024.102283DOI Listing

Publication Analysis

Top Keywords

exertional hypoxemia
8
shunting blood
8
permanent pacemaker-mediated
4
pacemaker-mediated exertional
4
hypoxemia patient
4
patient with ebstein
4
with ebstein anomaly
4
anomaly patients
4
patients ebstein
4
ebstein anomaly
4

Similar Publications

Background: Swimming-induced pulmonary edema (SIPE), also called immersion pulmonary edema, is a form of exertional pulmonary edema associated with swimming and/or water immersion without aspiration. Most case reports on SIPE feature young, healthy patients who were scuba-diving, surface swimming, snorkeling, or breath-hold diving before experiencing symptoms of dyspnea, chest pain/tightness, cough, and hemoptysis. The incidence of SIPE is thought to be between 0.

View Article and Find Full Text PDF

PERIPHERAL CHEMORECEPTOR, A NEW PLAYER IN METABOLIC SENSING DURING PHYSICAL EXERTION: A HYPOTHETICAL SCENARIO.

J Neurophysiol

December 2024

Exercise Applied Physiology Laboratory, Centro de Investigación en Fisiología y Medicina de Altura (FIMEDALT), Departamento Biomedico, Facultad de Ciencias de la Salud,Universidad de Antofagasta,, Antofagasta, Chile.

The cardiorespiratory and metabolic response to exercise has been associated with meeting the organism's metabolic demands during physical exertion. Of note, an incremental exercise is characterized by i) cardiodynamic phase related to cardiac output enhancement mainly determined by a positive chronotropic response, ii) ventilatory threshold one, associated with a significant contribution of cardiovascular and pulmonary ventilation, and iii) ventilatory threshold two, correlated with a tremendous increase in breathing and metabolic responses to exercise. Notably, it has been shown that the ventilatory response to exercise increases concomitantly with the release and accumulation of metabolites (i.

View Article and Find Full Text PDF
Article Synopsis
  • Ambulatory oxygen is vital for patients with idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD) who have low oxygen levels during physical activity, especially if traditional testing may miss their true needs.
  • A study reviewed treadmill exercise tests for 329 IPF patients and 2,343 COPD patients to measure their oxygen flow requirements, finding that IPF patients typically need more oxygen than COPD patients at peak exertion.
  • Notably, while some patients didn't need oxygen during moderate exercise, a significant portion (49% of IPF and 24% of COPD patients) required it when pushed to their highest level of exertion, highlighting the limitations of standard testing.
View Article and Find Full Text PDF
Article Synopsis
  • Anastomoses between pulmonary arteries and veins, which are common in adults, can lead to blood bypassing alveoli, causing hypoxaemia, especially in conditions like COVID-19 and influenza A.
  • A case of severe hypoxaemia linked to influenza A was poorly responsive to oxygen treatment and worsened with CPAP, indicating a significant intrapulmonary shunt contributing to the issue.
  • Understanding these shunts in viral infections can improve respiratory treatment strategies and help identify new therapeutic approaches to prevent the need for intubation.
View Article and Find Full Text PDF

The impact of caffeine and glucose supplementation in a hypoxic environment on endurance exercise performance remains inconclusive. The current study examined the effect of pre-exercise carbohydrate and caffeine supplementation on endurance exercise performance in an acute hypoxic environment. Eight healthy active young males participated in this double-blind, within-subjects crossover study.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!