AI Article Synopsis
- Paraguay is experiencing a new outbreak of Chikungunya virus, with reported severe cases confirmed through advanced testing methods.
- Two patients exhibited acute CHIKV infection with symptoms affecting multiple systems, resembling the inflammatory responses seen in cases of MIS-C related to COVID-19.
- Both patients were treated with IVIG and methylprednisolone, showing positive recovery, raising the question of whether this condition can be termed "Multisystem inflammatory syndrome associated with Chikungunya."
Article Abstract
Paraguay is currently facing a new outbreak of Chikungunya virus. This report summarizes two severe cases of Chikungunya (CHIKV) infection, confirmed by real-time reverse transcription polymerase chain reaction. We present the cases of patients with acute CHIKV infection and multisystem involvement, with fever, rash, abdominal pain, vomiting, myocarditis, and coronary artery anomalies, very similar to the cases described in MIS-C related to SARS-CoV-2 during the COVID-19 Pandemic. Both patients received IVIG and methylprednisolone, with good clinical response. In this setting of cytokine storm in Chikungunya, can we call it "Multisystem inflammatory syndrome associated with Chikungunya"?.
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| http://dx.doi.org/10.1016/j.reumae.2024.04.005 | DOI Listing |
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