AI Article Synopsis

  • The study compared body composition and motor function in children aged 6-12 years who were born large for gestational age (LGA) versus those born appropriate for gestational age (AGA).
  • Findings showed that LGA children had a higher fat mass index and lower gait deviation index compared to AGA children, suggesting potential risks for metabolic syndrome and gait issues.
  • Multiple regression analysis indicated that both being LGA at birth and fat mass index were key factors related to gait performance, emphasizing the importance of monitoring these variables in LGA children.

Article Abstract

Background: This cross-sectional study compared body composition and motor function between children who were born large for gestational age (LGA) and those born appropriate for gestational age (AGA) and to investigate the association between gait quality and other variables.

Methods: Body composition was determined using a bioelectrical impedance analyzer. Motor functions were assessed using one-leg standing time, timed up-and-go test, five times sit-to-stand test, and three-dimensional gait analysis. We compared the results between two groups. We performed multiple regression analysis to evaluate the association between gait deviation index and variables of LGA, fat mass index, and motor functions (adjusted for age and sex).

Results: Children aged 6-12 years who were born LGA at term (n = 23) and those who were born AGA at term (n = 147) were enrolled. The LGA group had a higher fat mass index (2.9 vs. 2.2, p = 0.006) and lower gait deviation index (91.4 vs. 95.4, p = 0.011) than the AGA group. On multiple regression analysis, gait deviation index was associated with being LGA and fat mass index.

Conclusions: In school-aged children who were born LGA, monitoring increased fat mass index and decreased gait deviation index could lessen the risk of metabolic syndrome and reduced gait function.

Impact: Children aged 6-12 years who were born large for gestational age (LGA) at term showed a higher fat mass index and lower gait deviation index than those who were born appropriate for gestational age at term. No significant differences in balance function or muscle strength were observed between groups. On multiple regression analysis, gait deviation index was associated with being LGA at birth and fat mass index. In school-aged children who were born LGA, monitoring increased fat mass index and decreased gait deviation index could lessen the risk of metabolic syndrome and reduced gait function.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11502499PMC
http://dx.doi.org/10.1038/s41390-024-03211-6DOI Listing

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