AI Article Synopsis
- - Recurrent implantation failure (RIF) poses challenges in assisted reproductive techniques due to issues with endometrial receptivity, highlighting the need for reliable tests to assess it during embryo transfer.
- - MicroRNAs (miRNAs) play essential roles in implantation and pregnancy, and their dysregulation can lead to reproductive issues like RIF.
- - This review aims to explore endometrial miRNAs as noninvasive biomarkers for predicting endometrial receptivity in patients experiencing recurrent implantation failure.
Article Abstract
Recurrent implantation failure (RIF) is a significant obstacle in assisted reproductive procedures, primarily because of compromised receptivity. As such, there is a need for a dependable and accurate clinical test to evaluate endometrial receptiveness, particularly during embryo transfer. MicroRNAs (miRNAs) have diverse functions in the processes of implantation and pregnancy. Dysregulation of miRNAs results in reproductive diseases such as recurrent implantation failure (RIF). The endometrium secretes several microRNAs (miRNAs) during the implantation period, which could potentially indicate whether the endometrium is suitable for in vitro fertilization (IVF). The goal of this review is to examine endometrial miRNAs as noninvasive biomarkers that successfully predict endometrium receptivity in RIF.
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| http://dx.doi.org/10.1016/j.cca.2024.119678 | DOI Listing |
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