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The impact of transcutaneous vagus nerve stimulation on anterior cingulate cortex activity in a cognitive control task.
Psychophysiology
January 2025
Biological Psychology Lab, Department of Psychology, School of Medicine and Health Sciences, Carl von Ossietzky University Oldenburg, Oldenburg, Germany.
Transcutaneous vagus nerve stimulation (tVNS) offers a non-invasive method to enhance noradrenergic neurotransmission in the human brain, thereby increasing cognitive control. Here, we investigate if changes in cognitive control induced by tVNS are mediated through locus coeruleus-induced modifications of neural activity in the anterior cingulate cortex. Young healthy participants engaged in a simple cognitive control task focusing on response inhibition and a more complex task that involved both response inhibition and working memory, inside a magnetic resonance imaging scanner.
View Article and Find Full Text PDFNeuromodulation for Headache Management in Pregnancy.
Curr Pain Headache Rep
January 2025
Department of Neurology - Headache Division, University of Miami Health, University of Miami School of Medicine, 1120 NW 14th Street, 13th Floor, Miami, FL, 33136, USA.
Purpose Of Review: Management of primary headache disorders during pregnancy is limited due to known teratogenicity or unknown safety of many currently available pharmaceutical therapies. Here, we explore the safety and efficacy of non-invasive neuromodulatory devices as another treatment modality for pregnant patients.
Recent Findings: There are six FDA-cleared, non-invasive neuromodulatory devices currently available for the management of headache that include remote electrical neuromodulation (REN), noninvasive vagal nerve stimulation (nVNS), external trigeminal nerve stimulation (eTNS), single-pulse transcranial magnetic stimulation (sTMS), and external concurrent occipital and trigeminal neurostimulation (eCOT-NS).
Transcutaneous Non-Invasive Vagus Nerve Stimulation: Changing the Paradigm for Stroke and Atrial Fibrillation Therapies?
Biomolecules
November 2024
Department of Anaesthesiology, Intensive Care, Emergency and Pain Medicine, Cerebrovascular Sciences and Neuromodulation, Würzburg University, 97080 Würzburg, Germany.
A new therapeutic approach, known as neuromodulation therapy-which encompasses a variety of interventional techniques meant to alter the nervous system in order to achieve therapeutic effects-has emerged in recent years as a result of advancements in neuroscience. Currently used methods for neuromodulation include direct and indirect approaches, as well as invasive and non-invasive interventions. For instance, the two primary methods of stimulating the vagus nerve (VN) are invasive VN stimulation (iVNS) and transcutaneous VN stimulation (tVNS).
View Article and Find Full Text PDFEffectiveness of non-invasive vagus nerve stimulation vs heart rate variability biofeedback interventions for chronic pain conditions: A systematic review.
Scand J Pain
January 2024
Crean College of Health and Behavioral Sciences, Department of Physical Therapy, Chapman University, Irvine, United States.
Objectives: Autonomic regulation has been identified as a potential regulator of pain via vagal nerve mediation, assessed through heart rate variability (HRV). Non-invasive vagal nerve stimulation (nVNS) and heart rate variability biofeedback (HRVB) have been proposed to modulate pain. A limited number of studies compare nVNS and HRVB in persons with chronic pain conditions.
View Article and Find Full Text PDFEffectiveness of non-invasive vagal nerve stimulation in Parkinson's disease: A comprehensive systematic review and meta-analysis.
J Clin Neurosci
December 2024
Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Background: Parkinson's disease (PD) is a debilitating neurodegenerative disorder characterized by movement impairments. Vagus nerve stimulation (VNS) is a non-invasive brain stimulation technique that has shown promise in treating various neurological conditions, including PD. This systematic review aimed to evaluate the existing evidence on the efficacy of nVNS in managing PD symptoms.
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