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| http://dx.doi.org/10.1007/s00428-024-03800-0 | DOI Listing |
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Serum Calcium Level in Patients with Essential Hypertension.
Mymensingh Med J
January 2025
Dr Md Mahbubor Rahman, Associate Professor, Department of Medicine, Shaheed Monsur Ali Medical College, Dhaka, Bangladesh; E-mail:
Hypertension is the leading risk factor for death and disability globally, particularly in Bangladesh. Serum calcium is supposed to be linked with the pathophysiology of hypertension, though various studies have shown contradictory results. Hence, this study was conducted to evaluate the role of serum calcium level in essential hypertensive patients.
View Article and Find Full Text PDFCorrection: Risk factors indicating immune-related adverse events with combination chemotherapy with immune checkpoint inhibitors and platinum agents in patients with non-small cell lung cancer: a multicenter retrospective study.
Cancer Immunol Immunother
December 2024
Department of Pharmacy, Clinical Research Institute, National Hospital Organization Kyushu Medical Center, Fukuoka, Japan.
Generalizability, robustness, and correction bias of segmentations of thoracic organs at risk in CT images.
Eur Radiol
December 2024
Department of Radiology, Antoni van Leeuwenhoek-The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Objective: This study aims to assess and compare two state-of-the-art deep learning approaches for segmenting four thoracic organs at risk (OAR)-the esophagus, trachea, heart, and aorta-in CT images in the context of radiotherapy planning.
Materials And Methods: We compare a multi-organ segmentation approach and the fusion of multiple single-organ models, each dedicated to one OAR. All were trained using nnU-Net with the default parameters and the full-resolution configuration.
Phase 1b/2 study of orally administered pexidartinib in combination with radiation therapy and temozolomide in patients with newly diagnosed glioblastoma.
Neurooncol Adv
November 2024
Huntsman Cancer Institute, Salt Lake City, UT, USA.
Background: Glioblastoma (GBM) has a median survival of <2 years. Pexidartinib (PLX3397) is a small-molecule inhibitor of CSF1R, KIT, and oncogenic FTL3, which are implicated in GBM treatment resistance. Results from glioma models indicate that combining radiation therapy (RT) and pexidartinib reduces radiation resistance.
View Article and Find Full Text PDFAssessing neonatal Sequential Organ Failure (nSOFA) scores in suspected late-onset neonatal sepsis among preterm infants: implications for morbidity and mortality.
BMJ Paediatr Open
December 2024
Department of Pediatrics, Division Neonatology, Amsterdam UMC Location AMC, Amsterdam, The Netherlands.
Background: The neonatal Sequential Organ Failure Assessment (nSOFA) score is an organ dysfunction score developed for predicting mortality risk in preterm neonates with proven late-onset neonatal sepsis (LONS) and necrotising enterocolitis. However, the utility of the nSOFA score in determining the risk of retinopathy of prematurity (ROP), bronchopulmonary dysplasia (BPD) or mortality in patients with suspected LONS is unknown.
Methods: We performed a dual-centre retrospective cohort study of preterm (gestational age <32 weeks) neonates suspected of LONS, from 2016 to 2020 at two neonatal intensive care units.
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