Additive manufacturing (3D-printing), in particular fused filament fabrication, presents a potential paradigm shift in the way electrochemical based biosensing platforms are produced, giving rise to a new generation of personalized and on-demand biosensors. The use of additive manufactured biosensors is unparalleled giving rise to unique customization, facile miniaturization, ease of use, economical but yet, still providing sensitive and selective approaches towards the target analyte. In this mini review, we focus on the use of fused filament fabrication additive manufacturing technology alongside different biosensing approaches that exclusively use antibodies, enzymes and associated biosensing materials (mediators) providing an up-to-date overview with future considerations to expand the additive manufacturing biosensors field.
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http://dx.doi.org/10.1039/d4ay00278d | DOI Listing |
J Phys Chem B
January 2025
Department of Computer and Information Sciences, Department of Materials Science and Engineering, University of Delaware, Newark, Delaware 19716, United States.
Liquid phase-separating proteins can form condensates that play an important role in spatial and temporal organization of biological cells. The understanding of the mechanisms that lead to the formation of protein condensates and their interactions with other biomolecules may lead to processing routes for soft materials with tailored geometry and function. Fused in sarcoma (FUS) is an example of a nuclear protein that forms stable complexes, and recent studies have highlighted its ability to wet actin filaments and bundle them into networks.
View Article and Find Full Text PDFMaterials (Basel)
January 2025
Faculty of Furniture Design and Wood Engineering, Transilvania University of Brasov, B-dul Eroilor, nr. 29, 500036 Brasov, Romania.
The present paper investigates the possibility of replacing the traditional L-type corner joint used in chair construction with a 3D printed connector, manufactured using the Fused Filament Fabrication (FFF) method and black PLA as filament. The connector was designed to assemble the legs with seat rails and stretchers, and it was tested under diagonal tensile and compression loads. Its performance was compared to that of the traditional mortise-and-tenon joint.
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December 2024
Faculty of Environmental Engineering, Lublin University of Technology, Nadbystrzycka 40B, 20-618 Lublin, Poland.
This study explores the application of materials used in 3D printing to manufacture the housings of non-invasive sensors employed in measurements using a TDR (Time Domain Reflectometry) meter. The research investigates whether sensors designed with 3D printing technology can serve as viable alternatives to conventional invasive and non-invasive sensors. This study focuses on innovative approaches to designing humidity sensors, utilizing Fused Deposition Modeling (FDM) technology to create housings for non-invasive sensors compatible with TDR devices.
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December 2024
Fraunhofer Institute for Machine Tools and Forming Technology IWU, Nöthnitzer Straße 44, 01187 Dresden, Germany.
Using a newly developed tool head with an additional rotational axis and a wire feed, wires can be directly processed in the fused filament fabrication (FFF) process. Thus, electrical structures such as conductive paths, coils, heating elements, or sensors can be integrated into polymer parts. However, the accuracy of the wire deposition in curved sections of the print track is insufficient.
View Article and Find Full Text PDFPolymers (Basel)
January 2025
Department of Statistics and Operations Research, Barcelona School of Industrial Engineering (ETSEIB), Universitat Politècnica de Catalunya, Av. Diagonal, 647, 08028 Barcelona, Spain.
Artificial neural network (ANN) models have been used in the past to model surface roughness in manufacturing processes. Specifically, different parameters influence surface roughness in fused filament fabrication (FFF) processes. In addition, the characteristics of the networks have a direct impact on the performance of the models.
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