Nutritional support therapy for liver transplantation in an adult-onset type II citrullinemia patient: a case report.

Front Nutr

Department of Pharmacy, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.

Published: March 2024

AI Article Synopsis

  • Liver transplantation is an effective treatment for adult-onset type II citrullinemia (CTLN2), but requires careful nutritional support for better patient outcomes.
  • Preoperative nutritional support should include a combination of enteral and parenteral nutrition, with daily energy intake recommendations between 35 to 40 kcal/kg.
  • Post-surgery, starting enteral nutrition quickly is crucial to restore intestinal function, and supplemental parenteral nutrition may be needed initially.

Article Abstract

Liver transplantation is an effective measure to treat adult-onset type II citrullinemia (CTLN2). Active and effective perioperative nutrition support is a very important treatment for the prognosis of such patients. In this paper, we analyzed the process, results, and outcome of nutritional support therapy in a case of CTLN2, and concluded that the perioperative nutritional support program for CTLN2 patients should be followed prior to surgery:1.because of the prevalence of severe malnutrition in CTLN2 patients, Enteral nutrition (EN) combined with Parenteral nutrition (PN) should be the first choice for nutritional support; 2. daily energy intake should be 35 ~ 40 kcal/kg; 3. the nutritional formula should be composed of low-carbohydrates and high medium-chain triglyceride (MCT). Postoperative: initiating EN as soon as possible is recommended to restore intestinal function and adjuvant PN might be taken into consideration in the early stage. The purpose of this case was to provide experience for the development and adjustment of the perioperative nutritional support regimen for CTLN2 patients.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11025469PMC
http://dx.doi.org/10.3389/fnut.2024.1364866DOI Listing

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