Long-Term Impairment From Irritant-Induced Occupational Asthma.

J Occup Environ Med

From the Doctoral Programme in Clinical Research, University of Helsinki, Helsinki, Finland (J.L.); Finnish Institute of Occupational Health, Helsinki, Finland (J.L., H.S., I.L.); Division of Medicine, Department of Pulmonary Diseases and Clinical Allergology, University of Turku, Turku, Finland (T.V.); Finnish Lung Health Association (FILHA), Helsinki, Finland (T.V.); and Varma Mutual Pension Insurance Company, Consultant Physicians, Helsinki, Finland (K.K.).

Published: July 2024

Objective: The aim of the study is to assess the long-term physical condition, health-related quality of life, employment, and work ability of irritant-induced asthma (IIA) patients.

Methods: Forty-three IIA patients completed a follow-up questionnaire a median of eight (interquartile range 4-11) years after asthma diagnosis. We compared their results with those of 43 low-molecular-weight (LMW) sensitizer-induced occupational asthma (OA) patients and those of 206 adult-onset asthmatics in the general population.

Results: Of the IIA patients, 40% reported depressive symptoms. Of the <65-year-olds, 56% were employed, of whom 39% assessed their work ability as limited. IIA patients had more difficulty climbing several flights of stairs than LMW-induced OA patients (70% vs 47%, OR = 4.83 95% CI: 1.51-15.47). Most of the IIA patients' outcomes were inferior to those of the adult-onset asthmatics in the general population.

Conclusions: IIA prognosis appeared poor but resembled that of LMW-induced OA.

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Source
http://dx.doi.org/10.1097/JOM.0000000000003120DOI Listing

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