Pediatric thyroid side effects of immune checkpoint inhibitors.

Trends Endocrinol Metab

Endocrine Pathology of Chronic and Post Cancer Diseases Unit, Bambino Gesù Children's Hospital, IRCCS Piazza Sant'Onofrio 4, 00165, Rome, Italy.

Published: September 2024

Immune checkpoint inhibitors (ICIs) are associated with multiple endocrine side effects, including thyroid disfunctions. In addition, the efficacy and safety profiles of ICIs in the pediatric population need clarification. Here, we discuss the main evidence regarding the efficacy and thyroid toxicities of ICIs in children.

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Source
http://dx.doi.org/10.1016/j.tem.2024.04.002DOI Listing

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