In 2023, six decades have elapsed since the first experimental work on the heart muscle was published, in which a member of the Institute of Physiology of the Czech Academy of Sciences participated as an author; Professor Otakar Poupa was the founder and protagonist of this research domain. Sixty years - more than half of the century - is certainly significant enough anniversary that is worth looking back and reflecting on what was achieved during sometimes very complicated periods of life. It represents the history of an entire generation of experimental cardiologists; it is possible to learn from its successes and mistakes. The objective of this review is to succinctly illuminate the scientific trajectory of an experimental cardiological department over a 60-year span, from its inaugural publication to the present. The old truth - historia magistra vitae - is still valid. Keywords: Heart, Adaptation, Development, Hypoxia, Protection.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11412335 | PMC |
| http://dx.doi.org/10.33549/physiolres.935337 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Cross- and Within-Language Associations Between Phonological, Lexical, and Grammatical Domains in Mandarin-English Bilingual Preschoolers in Singapore.
J Speech Lang Hear Res
January 2025
Department of Linguistics and Modern Languages, The Chinese University of Hong Kong, China.
Purpose: This study aims to examine the associations of phonological, lexical, and grammatical skills within and between languages in Mandarin-English bilingual preschoolers.
Method: Sixty-three Singaporean Mandarin-English bilingual children aged 3-5 years were assessed for articulation, receptive vocabulary, and receptive grammar using standardized instruments in English and compatible tools in Mandarin. Regression analyses were performed on each language outcome, with other language variables as predictors, controlling for age, nonverbal working memory, and home language environment.
Assessment of Erythrocytes Methotrexate Polyglutamate Three Levels in Psoriatic Patients Treated with Methotrexate Monotherapy and Their Association with Disease Response.
Indian J Clin Biochem
January 2025
Department of Dermatology, JIPMER, Puducherry, 06 India.
Unlabelled: Methotrexate is used to manage moderate to severe psoriasis and psoriatic arthritis. Methotrexate acts by inhibiting the enzymes involved in nucleotide synthesis. Methotrexate polyglutamates (MTXPGs) have a higher potency to inhibit Dihydrofolate reductase (DHFR), 5-aminoimidazole-4-carboxamide ribonucleotide transformylase (ATIC), and thymidylate synthase (TS), compared to naïve methotrexate.
View Article and Find Full Text PDFAnalgesic Efficacy Comparison Between Ultrasound-Guided Erector Spinae Plane Block and Retrolaminar Block in Patients Undergoing Modified Radical Mastectomy: A Randomized Controlled Trial.
Cureus
December 2024
Anaesthesiology, All India Institute of Medical Sciences, Raipur, Raipur, IND.
Introduction: Breast cancer is the most common cancer in females. Surgery is the gold standard therapy, with modified radical mastectomy (MRM) being the most commonly performed procedure for breast cancer. Management of postoperative pain after MRM poses a clinical challenge and hence receives utmost priority.
View Article and Find Full Text PDFMolecular Assay Versus Serology for Diagnosis of Scrub Typhus Among Patients With Acute Febrile Illness: A Retrospective Study.
Cureus
December 2024
Microbiology, Kalinga Institute of Medical Sciences, Bhubaneswar, IND.
Background And Objectives: The epidemiology of scrub typhus caused by has been growing in Odisha, India. The most common symptoms include fever, cough, lymphadenopathy, eschar, and rash. In India, enzyme-linked immunosorbent assays (ELISA) and DNA real-time polymerase chain reaction (DNA RT-PCR) are the most commonly used methods to diagnose scrub typhus.
View Article and Find Full Text PDFPain as a Symptom of Mental Health Conditions Among Undocumented Migrants in France: Results From a Cross-Sectional Study.
Int J Public Health
January 2025
Institut de Recherche et de Documentation en Économie de la Santé, Paris, France.
Objectives: This study aimed to explore the associations between mental health status and experienced pain among undocumented migrants (UMs) in France.
Methods: We used data from the multicentric cross-sectional "Premier Pas" study conducted in the Parisian and Bordeaux regions from February to April 2019. Participants over 18 years of age were recruited from sixty-three sites.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!