AI Article Synopsis
- Fungal infections in returning travelers are tough to identify because symptoms can be vague and the disease patterns change over time.
- This case details a traveler from Bangladesh who developed severe progressive disseminated histoplasmosis, needing mechanical ventilation due to respiratory issues.
- Key tests that helped identify the fungal infection included serum markers 1-3-β-D-glucan and galactomannan, with a final diagnosis confirmed using panfungal PCR from lung fluid samples.
Article Abstract
Fungal infections can be challenging to diagnose in returning travellers due to their non-specific clinical manifestations and changing epidemiology. We present a case of progressive disseminated histoplasmosis in a returning traveller from Bangladesh. The patient had a progressive and prolonged respiratory illness necessitating mechanical ventilatory support. The clue to potential fungal aetiology was provided by serum fungal markers - 1-3-β-D-glucan and galactomannan. Diagnosis was eventually made using panfungal PCR on bronchioalveolar lavage fluid.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11021948 | PMC |
| http://dx.doi.org/10.1016/j.mmcr.2024.100647 | DOI Listing |
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