Purpose: To explore the effect of AFN on knee function and complications in patients after TKA.
Methods: We evaluated 150 patients undergoing unilateral TKA, specifically including 102 patients with varying degrees of AFN after selection. They were divided into four groups based on AFN grade. About 48 patients did not produce AFN, 63 patients were grade I, 29 patients were grade II, and 10 patients were grade III. All patients were followed up for 24 months, and knee function, pain, complications, and other indicators were compared between the four groups. Correlation analysis and regression analysis were used to study the relationship between AFN and other indicators.
Results: Two cases of periprosthetic fractures (PPF) occurred in our study, with an incidence of 1.35%, which did not show a significant association with AFN. The changes in knee social score (ΔKSS), Western Ontario and McMaster Universities Osteoarthritis Index (ΔWOMAC), and postoperative anterior knee pain visual analog scale (VAS) score were higher in patients with AFN than in those without. Particularly, grades II and III AFN demonstrated superior efficacy. Pearson's correlation analysis showed that AFN grade is positively correlated with both ΔKSS and ΔWOMAC ( = 0.44, < 0.001), and AFN grade had a negative correlation with the anterior knee pain VAS ( = -0.250, < 0.05). In linear regression analysis, AFN grade was positively correlated with both ΔKSS ( = 5.974, 95% CI: 3.968-7.981, < 0.001) and ΔWOMAC ( = 6.356, 95% CI: 4.223-8.490, < 0.001). Besides that, there was a negative correlation between AFN grade and anterior knee pain ( = 5.974, 95% CI: 3.968-7.981, < 0.05).
Conclusion: Patients with grade II and III AFN who underwent TKA exhibited better knee function and lower levels of anterior knee pain post-surgery.
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http://dx.doi.org/10.1515/med-2024-0932 | DOI Listing |
Open Med (Wars)
April 2024
Orthopedic Department, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, Zhejiang, China.
Purpose: To explore the effect of AFN on knee function and complications in patients after TKA.
Methods: We evaluated 150 patients undergoing unilateral TKA, specifically including 102 patients with varying degrees of AFN after selection. They were divided into four groups based on AFN grade.
Trials
April 2022
Clinical Research Support Unit (HUB-IDIBELL: Bellvitge University Hospital & Bellvitge Biomedical Research Institute), Bellvitge University Hospital, L'Hospitalet de Llobregat, Barcelona, Spain.
Background: COVID-19 has quickly become a global pandemic with a substantial number of deaths and is a considerable burden for healthcare systems worldwide. Although most cases are paucisymptomatic and limited to the viral infection-related symptoms, some patients evolve to a second phase, with an impaired inflammatory response (cytokine storm) that may lead to acute respiratory distress syndrome and death. This is thought to be caused by increased bradykinin synthesis.
View Article and Find Full Text PDFIndian J Orthop
April 2022
Division of Orthopaedics, Trauma and Spine Surgery, Ganga Hospital, 313 Mettupalayam Road, Coimbatore, 641043 India.
Objective: The ipsilateral acetabulum and femur fracture (IAFF) is an uncommon entity. This combination challenges the surgeon in the optimal management of each injury component, fixation sequence, surgical approaches, implant choices and complications. Inappropriate approach for one fracture may affect the fixation of another or modify the overall outcome.
View Article and Find Full Text PDFInjury
March 2022
Orthopaedic Department, Hadassah Hebrew University Hospital, Jerusalem, Israel.
Introduction: Treatment of severe open femoral fractures with retrograde intramedullary nailing, raises concerns of septic arthritis of the knee due to its intra-articular entrance point. There is little evidence concerning the safety of retrograde femoral nailing (RFN) usage in these cases, and what evidence there is does not necessarily include severe open fractures. Furthermore, the outcome of ballistic injuries treated in this manner and a comparison with antegrade femoral nailing (AFN), is yet to be established.
View Article and Find Full Text PDFInt J Gynecol Pathol
April 2007
Department of Pathology, St. Luke's Hospital, St. Louis, Missouri 63141, USA.
The presence of mucin-containing signet-ring cells in an ovarian neoplasm is considered strong evidence for a metastatic rather than primary tumor. The clinicopathologic features of 2 ovarian adenofibromatous neoplasms with mucin-containing signet-ring cells (AFN-SRs), proven by the long-term follow-up of 10 and 15 years to be primary tumors, are presented as exceptions to this general guideline. Both of these tumors were initially strongly favored to be metastatic adenocarcinoma by expert consultants in gynecologic pathology, which underscores the diagnostic difficulty that these rare and unusual neoplasms can pose.
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