Effect of polymer concentration on the morphology of the PHPMAA--PLA graft copolymer nanoparticles produced by microfluidics nanoprecipitation.

Successful generation of micelles, vesicles, and/or worms with controllable sizes was achieved through the self-assembly process of the poly[-(2-hydroxypropyl)]methacrylamide--polylactide (PHPMAA--PLA) graft copolymer within a microfluidic channel. A product diagram was created to illustrate various morphologies associated with different polymer concentrations, all while maintaining a constant flow velocity ratio between water and the polymer solution.