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Clinical Variant of Serpentine Supravenous Hyperpigmentation Following Subcutaneous Bortezomib Injection.
HCA Healthc J Med
December 2024
University of North Texas Health Science Center at Fort Worth, Fort Worth, TX.
Introduction: Bortezomib is a reversible proteasome inhibitor that is a first-line chemotherapeutic agent for multiple myeloma. Bortezomib can be administered intravenously or subcutaneously with similar efficacy. Subcutaneous administration has fewer side effects.
View Article and Find Full Text PDFPseudoepitheliomatous hyperplasia misdiagnosed as cutaneous squamous cell carcinoma: a case report.
J Surg Case Rep
January 2025
Department of Dermatology, The First Affiliated Hospital of Ningbo University, 59 Liuting Street, Ningbo, Zhejiang 315010, China.
Pseudoepitheliomatous hyperplasia (PEH) is a rare histopathological reaction. Cases of PEH have been infrequently reported, and it's even rare to appear as a postsurgical complication. This case report describes the development of multiple masses and purulent discharge around an abdominal scar following surgery for hepatocellular carcinoma, which morphologically resembles squamous cell carcinoma (SCC), though pathology revealed no signs of malignancy.
View Article and Find Full Text PDFSevere palmoplantar keratoderma: a cutaneous complication from sub-optimally controlled type 2 diabetes.
Endocrinol Diabetes Metab Case Rep
January 2025
Summary: Palmoplantar keratoderma (PPK), characterised by excessive epidermal thickening of the skin on the palms and/or plantar surfaces of the feet, can be hereditary or acquired. Here, we report a case of a 53-year-old woman with a history of sub-optimally controlled diabetes mellitus presenting with fevers and decreased Glasgow Coma Scale (GCS) to a tertiary hospital. She was diagnosed with diabetic ketoacidosis (DKA), with blood glucose at 40 mmol/L and ketones at 7 mmol/L, in the setting of a methicillin-sensitive Staphylococcus aureus necrotising soft tissue back infection.
View Article and Find Full Text PDFMultiple cutaneous mast cell tumors displaying epitheliotropism in a male cat.
Can Vet J
January 2025
Department of Small Animal Clinical Sciences (Cormillot, Weissman, MacDonald-Dickinson) and Department of Veterinary Pathology (Dickinson), Western College of Veterinary MeDicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4.
A 16-year-old castrated male domestic medium-hair cat was referred for examination of multiple cutaneous mast cell tumors displaying epitheliotropism. Staging tests were negative for distant metastasis. Toceranib phosphate therapy was initiated.
View Article and Find Full Text PDFT cell malignancies after CAR T cell therapy in the DESCAR-T registry.
Nat Med
January 2025
Department of Hematology, University Hospital of Rennes, UMR U1236, INSERM, University of Rennes, French Blood Establishment, Rennes, France.
The risk of T cell malignancies after chimeric antigen receptor (CAR) T cell therapy is a concern, although the true incidence remains unclear. Here we analyzed the DESCAR-T registry database, encompassing all pediatric and adult patients with hematologic malignancies who received CAR T cell therapy in France since 1 July 2018. Of the 3,066 patients included (2,536 B cell lymphoma, 162 B cell acute lymphoblastic leukemia (ALL) and 368 multiple myeloma), 1,680 (54.
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