Oral health in individuals with bleeding disorders: A systematic review and meta-analysis.

Haemophilia

Division of Public Health Dentistry, CDER, -AIIMS, New Delhi, India.

Published: May 2024

AI Article Synopsis

  • A systematic review and meta-analysis were conducted to analyze oral health issues in individuals with bleeding disorders, highlighting the lack of comprehensive previous evaluations on this topic.
  • The study included 22 articles with 2422 subjects, assessing various oral health metrics and risks for bias in methodologies using established tools.
  • Results indicated that individuals with bleeding disorders had fair oral hygiene, lower dmft/DMFT scores, and emphasized the importance of managing oral bleeding during dental treatment.

Article Abstract

Background: Individuals with bleeding disorders have been reported to have a number of oral health issues due to varying conditions. A comprehensive evaluation of the different oral health conditions has not been carried out in the past. This systematic review and meta-analysis was carried out to collate and critically analyse existing research, and provide a comprehensive overview of the current state of knowledge on oral health.

Methods: A comprehensive search was conducted in electronic databases, including PubMed, Scopus and Embase, in October 2023. No restriction on time frame or language was applied. The risk of bias for cross-sectional studies was assessed using the Agency for Healthcare Research and Quality (AHRQ) tool, and case control studies were assessed using the New Castle Ottawa Scale (NOS).

Results: Twenty-two articles were included in the final analysis with a total sample size of 2422 subjects. Of the 22 articles assessed, nine quantitative assessments were included in the Meta analysis. Pooled data analysis was carried out. A total of 13 studies reported medium risk whereas the remaining nine studies showed low risk of bias. The weighted mean DMFT scores in individuals with bleeding disorders were found to be 2.43 [0.62. 4.24], mean dmft was 2.79 [1.05, 4.53] and mean OHI-S was reported to be 1.79 [1.00, 2.57], respectively.

Conclusion: The findings emphasize that these individuals have fair oral hygiene and lower dmft/DMFT scores. Oral bleeding emerged as an important oral health component to be cautiously dealt with particularly during the stages of exfoliation/shedding.

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Source
http://dx.doi.org/10.1111/hae.15009DOI Listing

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