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Two new chemical constituents from the aerial parts of . | LitMetric

Two new chemical constituents from the aerial parts of .

Nat Prod Res

Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou, China.

Published: April 2024

has been historically employed as a conventional botanical insecticide and a plant of medicinal significance. A new dihydroagarofuran sesquiterpene () and a new acyclic compound (), along with seven known compounds (), have been isolated from the aerial parts of . The identification of the structures of novel compounds were accomplished through comprehensive spectroscopic analyses, encompassing HRESIMS, NMR, UV, IR, and a comparative analysis with spectroscopic data from compounds previously characterised. In - bioassay, compound exhibited significant inhibitory activity for NO release in LPS-induced RAW 264.7 cells, with an IC value of 15.7 M.

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Source
http://dx.doi.org/10.1080/14786419.2024.2342000DOI Listing

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