SARS-CoV-2 antibodies in adolescents living with perinatally acquired HIV.

S Afr J Infect Dis

Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

Published: March 2024

AI Article Synopsis

  • The study focuses on adolescents living with perinatally acquired HIV and their co-infection with COVID-19, highlighting limited data on this population.* -
  • A descriptive analysis was conducted on 53 adolescents who were tested for COVID-19 antibodies, revealing that 53% tested positive despite only one reporting prior symptomatic infection.* -
  • The research enhances knowledge about SARS-CoV-2 infection and vaccination strategies in HIV-positive adolescents, contributing valuable insights for healthcare practices.*

Article Abstract

Unlabelled: Data on children and adolescents with HIV and coronavirus disease 2019 (COVID-19) co-infection are limited. Clinical and antibody data related to COVID-19 infection in adolescents living with perinatally acquired HIV (ALPHIV) and originally enrolled in the Children with HIV Early Antiretroviral Therapy (CHER) study were collected. We present a descriptive analysis of 53 ALPHIV who were tested for anti-SARS-CoV-2 antibodies. Just over half (53%) of the adolescents tested had positive anti-SARS-CoV-2 antibodies with only one participant describing a prior history of possible symptomatic infection.

Contribution: The study contributes to the understanding of SARS-CoV-2 infection and vaccination practices in HIV-positive adolescents.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11019109PMC
http://dx.doi.org/10.4102/sajid.v39i1.579DOI Listing

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