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| http://dx.doi.org/10.3348/kjr.2023.1306 | DOI Listing |
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Deciphering key nano-bio interface descriptors to predict nanoparticle-induced lung fibrosis.
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State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Suzhou Medical School, Soochow University, Suzhou, Jiangsu, 215123, China.
Background: The advancement of nanotechnology underscores the imperative need for establishing in silico predictive models to assess safety, particularly in the context of chronic respiratory afflictions such as lung fibrosis, a pathogenic transformation that is irreversible. While the compilation of predictive descriptors is pivotal for in silico model development, key features specifically tailored for predicting lung fibrosis remain elusive. This study aimed to uncover the essential predictive descriptors governing nanoparticle-induced pulmonary fibrosis.
View Article and Find Full Text PDFMacro-Micro Properties of Remodeled Waste Slurry Under Freeze-Thaw Cycles.
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January 2025
School of Civil and Transportation Engineering, Hebei University of Technology, Xiping Road 5340, Tianjin 300401, China.
Waste slurry, a major by-product of urban construction, is produced in rapidly increasing volumes each year. Dehydrated waste slurry has potential as a roadbed material; however, its performance in freeze-thaw environments, which can induce frost heave and thaw settlement, and the mechanism of the influence of freeze-thaw cycles on its macro and micro properties are still unclear and need thorough investigation. This study explores the macroscopic and microscopic properties of waste slurry subjected to freeze-thaw cycles.
View Article and Find Full Text PDFEffects of Far-Red Light and Ultraviolet Light-A on Growth, Photosynthesis, Transcriptome, and Metabolome of Mint ( Briq.).
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College of Ecological Technology and Engineering, Shanghai Institute of Technology, Shanghai 201418, China.
To investigate the effects of different light qualities on the growth, photosynthesis, transcriptome, and metabolome of mint, three treatments were designed: (1) 7R3B (70% red light and 30% blue light, CK); (2) 7R3B+ far-red light (FR); (3) 7R3B+ ultraviolet light A (UVA). The results showed that supplemental FR significantly promoted the growth and photosynthesis of mint, as evidenced by the increase in plant height, plant width, biomass, effective quantum yield of PSII photochemistry (F'/F'), maximal quantum yield of PSII (F/F), and performance index (PI). UVA and CK exhibited minimal differences.
View Article and Find Full Text PDFPopulation and Co-Occurrence Characteristics of Diagnoses and Comorbidities in Coronary Artery Disease Patients: A Case Study from a Hospital in Guangxi, China.
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Department of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China.
Coronary artery disease (CAD) remains a major global health concern, significantly contributing to morbidity and mortality. This study aimed to investigate the co-occurrence patterns of diagnoses and comorbidities in CAD patients using a network-based approach. A retrospective analysis was conducted on 195 hospitalized CAD patients from a single hospital in Guangxi, China, with data collected on age, sex, and comorbidities.
View Article and Find Full Text PDFIntegrative Multi-Omics Analysis Reveals Critical Molecular Networks Linking Intestinal-System Diseases to Colorectal Cancer Progression.
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Suzhou Research Center of Medical School, Suzhou Hospital, Affiliated Hospital of Medical School, Nanjing University, Suzhou 215163, China.
: Colorectal cancer (CRC) frequently co-occurs with intestinal system diseases (ISDs), yet their molecular interplay remains poorly understood. We employed a comprehensive bioinformatics approach to elucidate shared genetic signatures and pathways between CRC and ISDs. : We systematically analyzed 12 microarray and RNA-seq datasets encompassing 989 samples across seven ISDs and CRC.
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