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Comparative effectiveness of angioembolization versus open surgery in patients with blunt splenic injury. | LitMetric

AI Article Synopsis

  • The study compares the safety and effectiveness of transcatheter splenic artery embolization (SAE) to open surgery in patients with blunt splenic injury (BSI) using data from 2004 to 2019.
  • After analyzing 2,192 patients, results showed that in-hospital mortality rates were similar for both SAE (11.6%) and open surgery (11.2%).
  • However, SAE resulted in significantly better spleen salvage rates (87.1%) compared to open surgery (32.1%), indicating SAE's superior outcome in preserving spleen function.

Article Abstract

The effectiveness and safety of transcatheter splenic artery embolization (SAE) compared to those of open surgery in patients with blunt splenic injury (BSI) remain unclear. This retrospective cohort-matched study utilized data from the Japan Trauma Data Bank recorded between 2004 and 2019. Patients with BSI who underwent SAE or open surgery were selected. A propensity score matching analysis was used to balance the baseline covariates and compare outcomes, including all-cause in-hospital mortality and spleen salvage. From 361,706 patients recorded in the data source, this study included 2,192 patients with BSI who underwent SAE or open surgery. A propensity score matching analysis was used to extract 377 matched pairs of patients. The in-hospital mortality rates (SAE, 11.6% vs. open surgery, 11.2%, adjusted relative risk (aRR): 0.64; 95% confidence interval [CI]: 0.38-1.09, p = 0.10) were similar in both the groups. However, spleen salvage was significantly less achieved in the open surgery group than in the SAE group (SAE, 87.1% vs. open surgery, 32.1%; aRR: 2.84, 95%CI: 2.29-3.51, p < 0.001). Survival rates did not significantly differ between BSI patients undergoing SAE and those undergoing open surgery. Nonetheless, SAE was notably associated with a higher likelihood of successful spleen salvage.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11021531PMC
http://dx.doi.org/10.1038/s41598-024-59420-wDOI Listing

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