This work presents an overview of the evolution of mathematical modeling applied to the context of epidemics and the advances in modeling in epidemiological studies. In fact, mathematical treatments have contributed substantially in the epidemiology area since the formulation of the famous SIR (susceptible-infected-recovered) model, in the beginning of the 20th century. We presented the SIR deterministic model and we also showed a more realistic application of this model applying a stochastic approach in complex networks. Nowadays, computational tools, such as big data and complex networks, in addition to mathematical modeling and statistical analysis, have been shown to be essential to understand the developing of the disease and the scale of the emerging outbreak. These issues are fundamental concerns to guide public health policies. Lately, the current pandemic caused by the new coronavirus further enlightened the importance of mathematical modeling associated with computational and statistical tools. For this reason, we intend to bring basic knowledge of mathematical modeling applied to epidemiology to a broad audience. We show the progress of this field of knowledge over the years, as well as the technical part involving several numerical tools.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482738 | PMC |
http://dx.doi.org/10.1007/s40863-021-00268-7 | DOI Listing |
Curr Protoc
January 2025
Cancer Prevention and Control Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
Mesothelioma is a lethal cancer of the serosal lining of the body cavities. Risk factors include environmental and genetic factors. Asbestos exposure is considered the principal environmental risk factor, but other carcinogenic mineral fibers, such as erionite, also have a causal role.
View Article and Find Full Text PDFOrg Lett
January 2025
School of Pharmacy, Guizhou University of Traditional Chinese Medicine, Guiyang 550025, China.
In this work, coixalkyne A (), a natural polynuclear calcium complex with a novel cross-shaped molecular architecture, was isolated from L. along with the undescribed analogue coixalkyne B (). Their structures were identified by means of NMR spectroscopy, ECD calculations, and single-crystal X-ray diffraction.
View Article and Find Full Text PDFMol Med Rep
March 2025
State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, SAR 999078, P.R. China.
Subarachnoid hemorrhage (SAH), a prevalent cerebrovascular condition associated with a high mortality rate, frequently results in neuronal apoptosis and an unfavorable prognosis. The adjunctive use of traditional Chinese medicine (TCM) with surgical interventions exerts a therapeutic impact on SAH, potentially by facilitating apoptosis. However, the mechanism by which TCM mediates apoptosis following SAH remains unclear.
View Article and Find Full Text PDFFront Immunol
January 2025
Department of Dermatology, Graduate School of Medicine, Osaka City University, Osaka, Japan.
Introduction: Atopic dermatitis (AD) is a common and relapsing skin disease characterized by skin barrier dysfunction, inflammation, and chronic pruritus. Both cutaneous barrier dysfunction and immune dysregulation are critical etiologies of the pathology of AD. Although various anti-inflammatory pharmacological agents, including cytokine inhibitors and signaling pathway blockers, have been developed recently, keeping the skin clean is of utmost importance in maintaining physiological cutaneous barrier function and avoiding an AD flare.
View Article and Find Full Text PDFHeliyon
January 2025
Alanya Alaaddin Keykubat University, Rafet Kayis Engineering Faculty, Department of Engineering Basic Science, 07450, Alanya, Antalya, Turkiye.
Removal of Rhodamine B (RhB) from aqueous solutions was performed by the batch adsorption process. Colemanite was characterized as an adsorbent by Fourier Transform Infrared Spectroscopy (FTIR), X-Ray Diffraction (XRD) and X-Ray Fluorescence (XRF). The effects of contact time, the effect of the initial concentration of the dye, the amount of adsorbent and temperature parameters on the removal of RhB were investigated.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!