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| http://dx.doi.org/10.4081/dr.2023.9802 | DOI Listing |
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Risk factors of Hypersensitivity Reactions to Carboplatin: A Systematic Review and Meta-analysis.
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December 2024
College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea. Electronic address:
Background: The development of hypersensitivity reactions (HSRs) to carboplatin can interrupt anticancer treatment and may shorten patient survival. Several studies have evaluated the risk factors for carboplatin HSRs, but the results have been inconclusive.
Objective: This systematic review and meta-analysis aim to establish a consensus on the risk factors of HSRs to carboplatin in cancer patients.
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Department of Medical Genetics, Faculty of Medicine, Erciyes University, Kayseri, Turkey.
In most cases there is a single etiological factor causing neuromotor developmental delay and epilepsy while sometimes more than one gene may be involved. These include the autosomal recessive inherited CAMSAP1 gene, which is associated with cortical developmental malformations such as pachygyria and lissencephaly and the autosomal dominant inherited NBEA gene, which plays crucial roles in vesicle trafficking as well as synapse structure and function. Loss of function of both genes together is a well-known disease mechanism.
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Universidade Vale do Rio Doce, Governador Valadares, Minas Gerais, Brazil.
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We experienced a case of a patient with a history of pacemaker implantation who was found to have lung cancer just behind the pacemaker. She was an 80-year-old woman with a history of valve replacement, pacemaker implantation, and sarcoidosis. Computed tomography showed a ground-glass opacity of 1.
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