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Polysaccharide Hydrogel-Assisted Biosensing Platforms for Point-of-Care Use.
Biosensors (Basel)
January 2025
Department of Biomedical Laboratory Science, Daegu Health College, Chang-ui Building, 15 Yeongsong-ro, Buk-gu, Daegu 41453, Republic of Korea.
Point-of-care (POC) use is one of the essential goals of biosensing platforms. Because the increasing demand for testing cannot be met by a centralized laboratory-based strategy, rapid and frequent testing at the right time and place will be key to increasing health and safety. To date, however, there are still difficulties in developing a simple and affordable, as well as sensitive and effective, platform that enables POC use.
View Article and Find Full Text PDFProvision of retroperitoneal sarcoma services in England: The case for centralisation to high volume centres.
Eur J Surg Oncol
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Sarcoma Unit, Royal Marsden NHS Foundation Trust, United Kingdom.
Comparative technoeconomic analysis of centralised and decentralised water source heat pump systems using CATHeaPS.
Heliyon
January 2025
James Watt School of Engineering, University of Glasgow, Glasgow, G12 8QQ, UK.
In the efforts to decarbonise the heat sector, heat pumps can offer a cost-effective transition away from fossil fuels. Water Source Heat Pumps (WSHP) can be utilised in cases where ambient water sources (river, ground water, abandoned mines water) are present. However, the economic benefits of different levels of heat pump centralisation as well as their comparative advantages over other decentralised options such as individual Air Source Heat Pumps (ASHP) or Gas Boilers (GB) remain uncertain and further investigations are necessary to fully assess their potential.
View Article and Find Full Text PDF[Analysis of clinical features and prognostic factors of focal cerebral arteriopathy in children].
Zhonghua Er Ke Za Zhi
January 2025
Department of Neurology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing100045, China.
To summarize the clinical characteristics of focal cerebral arteriopathy (FCA) in children, and to analyze its influencing factor of prognosis. A retrospective cohort study was conducted. Clinical data from 40 children with FCA who were hospitalized at the Department of Neurology, Beijing Children's Hospital, Capital Medical University, from September 2015 to August 2024 were collected.
View Article and Find Full Text PDFDeveloping a cost-effective and efficient safety case management solution for data coordinating center projects.
Contemp Clin Trials
January 2025
RTI International Center for Clinical Research, 3040 East Cornwallis Road, P.O. Box 12194, Research Triangle Park, NC 27709-2194, USA. Electronic address:
A centralized safety function can support multiple clinical trials and provide efficient, standardized processes for the management of serious adverse events. From 2017 to 2022, the centralized safety desk used pharmacovigilance software compliant with FDA regulations, including 21 CFR Part 11. This software assisted with processing safety cases for regulated clinical trials, including allowing capture of event data, and provided process flow management, documentation storage, and transmission of safety reports to FDA.
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