AI Article Synopsis
- The study analyzed catheter ablation success rates and complications in 591 patients with cardiac pacemakers compared to 7,393 patients without them, finding that patients with pacemakers were generally older and had more health issues.
- One-year mortality rates were higher in the pacemaker group (2.4%) versus the non-pacemaker group (1.3%), along with increased risks of re-hospitalization and combined cardiovascular events.
- Despite these increased risks, the rate of procedural success was high (98.8%) for those with pacemakers, and serious device-related complications were very low (0.4%).
Article Abstract
Background: Catheter ablation of atrial fibrillation and atrial flutter is routinely performed in patients with implantable devices. The aim of the present study was to assess success rates and potential complications in a large registry cohort of patients with cardiac pacemakers.
Methods And Results: The German Ablation Registry is a nationwide, prospective registry with a 1-year follow-up investigating patients who underwent catheter ablation of supraventricular arrhythmias in 51 German centers. The present analysis focussed on the presence of cardiac pacemakers in 591 patients undergoing catheter ablation of atrial fibrillation or atrial flutter. These were compared to 7393 patients without a pacemaker. Patients with pacemakers were significantly older and presented more comorbidities like diabetes, renal failure, cardiovascular disease, or previous stroke. One-year mortality (2.4% vs. 1.3%, p = 0.022) and a combined endpoint of death, myocardial infarction, and stroke (3.6% vs. 2.1%, p = 0.014) were significantly elevated in patients with pacemakers. Re-hospitalization was also more common in patients with a pacemaker (53.3% vs. 45.0%, p < 0.01). After adjustment for important comorbidities, pre-existing pacemaker systems did not show any negative effect. Procedural success was reported in 98.8% vs. 98.4% (p = 0.93). Device-related complications were only observed in 0.4% of patients with pacemakers.
Conclusion: Patients with pacemaker systems undergoing catheter ablation of atrial fibrillation or atrial flutter demonstrate an increased risk of death, cardiovascular events, and re-hospitalization. This observation can be largely attributed to an older patient population and an increased rate of comorbidities.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s00392-024-02449-8 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Clinical Profile and Management of Wolf-Parkinson White Syndrome and Asymptomatic Pre-Excitation Carriers in Africa: A Multicenter Pan African Registry From 17 Countries.
J Cardiovasc Electrophysiol
January 2025
Douala Gyneco-obstetric and Pediatric Hospital/University of Douala, Douala, Cameroon.
Article Synopsis
- The study explores the management and diagnosis of Wolf-Parkinson White Syndrome (WPW) and asymptomatic pre-excitation in Africa, highlighting a lack of data in the region.
- Conducted in 20 centers across 17 African countries, the research involved 541 participants and focused on symptomatology, treatment approaches, and the impact of local health dynamics on care.
- Results indicated that a vast majority were diagnosed with WPW, with significant regional differences in treatment options and effectiveness, showing that Northern and Southern Africa have more advanced practices compared to other areas.
Typical Atrial Flutter: A Practical Review.
J Cardiovasc Electrophysiol
January 2025
Cardiology Division, Geneva University Hospitals, Geneva, Switzerland.
Typical atrial flutter (AFL), defined as cavotricuspid isthmus (CTI)-dependent macro-re-entrant atrial tachycardia, often causes debilitating symptoms, and is associated with increased incidence of atrial fibrillation, stroke, heart failure, and death. Typical AFL occurs in patients with atrial remodeling and shares risk factors with atrial fibrillation. It is also common in patients with a history of prior heart surgery or catheter ablation.
View Article and Find Full Text PDFIdiopathic Annular Ventricular Arrhythmias.
Arrhythm Electrophysiol Rev
December 2024
Department of Medicine, Division of Cardiovascular Medicine, Vanderbilt University Medical Center Nashville, TN, US.
Idiopathic arrhythmias originating from the mitral and tricuspid annuli are commonly encountered in clinical practice. This review focuses on distinguishing features of ventricular arrhythmias arising from these structures and the importance of distinguishing idiopathic arrhythmias from those associated with structural heart disease. Each region along the mitral and tricuspid annuli (including the cardiac crux and para-Hisian region) is then discussed separately, with a particular emphasis on the ablation strategies and pitfalls for each.
View Article and Find Full Text PDFTheoretical and Practical Aspects of the Nonlinear Dynamics' Methods of Heart Rate Variability Analyses in Tachyarrhythmia Patients Underwent Radiofrequency Catheter Ablation.
Cardiovasc Eng Technol
January 2025
Department of Biomedical Engineering, Northwestern University, Chicago, IL, USA.
Purpose: This study explores the use of heart rate variability (HRV) analysis, a noninvasive technique for assessing the autonomic nervous system, by applying nonlinear dynamics and chaos theory to detect chaotic behavior in RR intervals and assess cardiovascular health.
Methods: Employing the "System Analysis of Heart Rate Dynamics" (SADR) program, this research combines chaos analysis with the short-time Fourier transform to assess nonlinear dynamic parameters in HRV. It includes constructing phase portraits in Takens space and calculating measures of chaos to identify deterministic chaos indicators.
Incidence, Mechanism, and Management of Atrial Ablation Procedure Complications: A Literature Review.
Cardiol Rev
December 2024
Departments of Cardiology and Medicine, Westchester Medical Center, New York Medical College, Valhalla, NY.
Article Synopsis
- The popularity of atrial catheter ablation has surged as a leading treatment for supraventricular tachycardias, praised for its safety and effectiveness.
- Complications can occur at various stages, including vascular, thromboembolic, and mechanical issues, with atrial fibrillation ablation being notably riskier due to its complexity.
- Strategies to minimize risks involve advanced techniques like optimized anticoagulation and esophageal temperature monitoring, while emerging methods like pulsed-field ablation show promise for improved safety, pending further research.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!