AI Article Synopsis
- The study investigates the link between social isolation (SI) and hypertension, focusing on how this relationship evolves from adolescence into early middle adulthood, using a comprehensive dataset spanning from 1994 to 2018.
- Individuals experiencing SI in young adulthood or early middle adulthood have higher chances of developing hypertension later, with specific odds ratios indicating significant risk increases.
- The findings underscore the importance of targeting social isolation early in life to potentially prevent hypertension and related cardiovascular issues later on.
Article Abstract
Background: Most studies have used cross-sectional or limited follow-up data to evaluate the relationship between social isolation (SI) and hypertension in older populations. The objective of this analysis was to examine the relationship between longitudinal SI and hypertension in a younger population.
Methods And Results: The present analysis used data from waves I to V of the National Longitudinal Study of Adolescent to Adult Health (1994-2018) and logistic regression models to describe the association of timing, duration, and transitional patterns of SI with hypertension in early middle adulthood. Models were adjusted for demographic variables and adolescent socioeconomic and health-related confounders. SI was higher across life stages among individuals with hypertension (adolescence: 38% versus 35%, young adulthood: 52% versus 44%, and early middle adulthood: 61% versus 52%). Individuals who were socially isolated in young adulthood or early middle adulthood had greater odds of hypertension in early middle adulthood than those who were not (odds ratio [OR], 1.30 [95% CI, 1.07-1.56]; OR, 1.42 [95% CI, 1.15-1.76], respectively). Early middle adulthood hypertension was significantly associated with persistent SI across all life stages and for those who moved into persistent SI after adolescence (OR, 1.40 [95% CI, 1.02-1.93]; OR, 1.61 [95% CI, 1.18-2.19], respectively).
Conclusions: SI in young or early middle adulthood significantly increased the odds of hypertension, as did moving into SI and the accumulation of SI across life stages. Our analysis provides insights regarding timing for effective interventions to reduce hypertension earlier in the life course, which may prevent future adverse cardiovascular-related events.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11179928 | PMC |
| http://dx.doi.org/10.1161/JAHA.123.030403 | DOI Listing |
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