AI Article Synopsis

  • Status dystonicus is a severe form of dystonia that can lead to life-threatening situations if not treated quickly, and the article presents guidelines for managing both worsening and refractory cases, particularly in children.
  • The guidelines offer a step-by-step approach for assessing and treating status dystonicus, aiming for better recognition, treatment standardization, and interdisciplinary collaboration.
  • Additionally, the recommendations emphasize incorporating new advancements in genomics and neuromodulation, supporting research, and improving patient outcomes across multiple centers.

Article Abstract

Status dystonicus is the most severe form of dystonia with life-threatening complications if not treated promptly. We present consensus recommendations for the initial management of acutely worsening dystonia (including pre-status dystonicus and status dystonicus), as well as refractory status dystonicus in children. This guideline provides a stepwise approach to assessment, triage, interdisciplinary treatment, and monitoring of status dystonicus. The clinical pathways aim to: (1) facilitate timely recognition/triage of worsening dystonia, (2) standardize supportive and dystonia-directed therapies, (3) provide structure for interdisciplinary cooperation, (4) integrate advances in genomics and neuromodulation, (5) enable multicenter quality improvement and research, and (6) improve outcomes. © 2024 International Parkinson and Movement Disorder Society.

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Source
http://dx.doi.org/10.1002/mds.29794DOI Listing

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