AI Article Synopsis
- Apraxia of eyelid opening (AEO) is a rare symptom in patients with Parkinson's disease (PD), often complicating treatment.
- A case study highlights a 64-year-old woman with PD who initially responded to medication but developed AEO and blepharospasm at age 69, with other treatments failing to help.
- Trihexyphenidyl (THP) eventually led to significant improvement in her AEO by age 73, suggesting THP's potential effectiveness in managing this specific symptom.
Article Abstract
Apraxia of eyelid opening (AEO) is occasionally seen in Parkinson's disease (PD) or related diseases. However, many clinicians have trouble with the management of AEO by Parkinsonism. In this report, we describe a case of AEO in Parkinsonism improved by trihexyphenidyl (THP). The patient was a 64-year-old woman, who was previously healthy but developed bradykinesia. She was clinically diagnosed as PD due to an L-dopa challenge test, but no other detailed tests were performed. She started antiparkinsonian medications and her symptoms were improved at an early phase. However, her motor symptoms were gradually exacerbated over time, and antiparkinsonian medications were dosed up. At 69 years old, blepharospasm and AEO developed. Although other antiparkinsonian medications did not improve her AEO, THP cured AEO dramatically at 73 years old. In this report, we discuss a mechanism of AEO by Parkinsonism and the pathway of THP for the improvement of AEO.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11016287 | PMC |
| http://dx.doi.org/10.7759/cureus.56232 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!