AI Article Synopsis

  • A 70-year-old Caucasian male was diagnosed with herpes zoster ophthalmicus, experiencing multiple ocular issues such as conjunctivitis, corneal infiltrates, and uveitis over a 6-month follow-up period.
  • The condition arises from the reactivation of the varicella-zoster virus affecting the trigeminal nerve, with common ocular symptoms including conjunctivitis and episcleritis.
  • Standard treatment involves antivirals like acyclovir, while prevention is achievable through vaccines like Zostavax and Shingrix; the patient's final visual acuity remained satisfactory despite the severity of his manifestations.

Article Abstract

Our purpose was to present a case of a patient diagnosed with herpes zoster ophthalmicus with multiple ocular manifestations. A 70-year-old Caucasian male presented to the hospital for headache and skin hyperesthesia on the scalp and forehead on the left side. The diagnoses of herpes zoster ophthalmicus and acute conjunctivitis were made for the left eye. The patient was followed up for 6 months and during that period the following diagnoses were made for the same eye: peripheral sterile corneal infiltrates, episcleritis, and hypertensive anterior uveitis. Herpes zoster ophthalmicus occurs when the reactivation of the dormant virus involves the ophthalmic division of the trigeminal nerve. The most frequent ocular presentations are conjunctivitis, keratitis, uveitis, episcleritis, and scleritis. The standard therapy consists of antivirals, such as acyclovir, valacyclovir, and famciclovir to limit the replication of the virus. The patient's risk factors, the course of treatment, and the severity of the disease, all affect the prognosis, which is highly variable. Prevention of the disease consists of vaccination with one of the following two vaccines, Zostavax and Shingrix. Final visual acuity for the left eye remained 1 despite numerous manifestations of the disease. VZV = Varicella-zoster virus, BCVA = best-corrected visual acuity, OU = both eyes, OD = right eye, OS = left eye, IOP = intraocular pressure, NCT = non-contact tonometer, ZVX = Zostavax vaccine.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11007559PMC
http://dx.doi.org/10.22336/rjo.2024.16DOI Listing

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