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We describe 157 cases of Trichophyton indotineae infection in the United Kingdom, mostly in patients linked to southern Asia. T. indotineae is spreading in the United Kingdom and accounts for 38% of dermatophyte isolates referred to the UK National Mycology Reference Laboratory.
View Article and Find Full Text PDFChinese expert consensus on management of antifungal-resistant dermatophytoses (2024 edition).
Mycoses
September 2024
Department of Medical Mycology, Institute of Dermatology and Hospital for Skin Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, China.
Article Synopsis
- * Cases of ARD infections have been reported in China, highlighting the risk of spreading these resistant strains among humans, complicating diagnosis and treatment.
- * Experts from various medical fields collaborated to create consensus guidelines, aiming to enhance awareness of dermatophyte drug resistance and provide practical recommendations for diagnosis, treatment, prevention, and control of ARD infections.
Antifungal-resistant dermatophyte infections have recently emerged as a global public health concern. A survey of US infectious diseases specialists found that only 65% had heard of this issue and just 39% knew how to obtain testing to determine resistance. Increased clinician awareness and access to testing for antifungal-resistant dermatophytosis are needed.
View Article and Find Full Text PDFAntifungal Patterns of Dermatophytes: A Pathway to Antifungal Stewardship in Eastern India.
Cureus
July 2024
Microbiology, Rajendra Institute of Medical Sciences, Ranchi, IND.
Background Dermatophytosis is a superficial fungal infection caused by a group of pathogenic keratinophilic fungi. The increase in the incidence of superficial fungal infections, combined with the emergence of antifungal resistance, represents both a global health challenge and a considerable economic burden. Recent years have witnessed a surge in dermatophytosis cases, accompanied by the emergence of antifungal-resistant strains.
View Article and Find Full Text PDFA systematic review on the emergence of terbinafine-resistant Trichophyton indotineae in Europe: Time to act?
J Eur Acad Dermatol Venereol
July 2024
Division of Microbiology, Department of Pathology, Faculty of Medicine, University of Porto, Porto, Portugal.
Background: There is a recent growing global concern regarding the rise in antifungal resistance of dermatophytosis. The emergence of terbinafine-resistant Trichophyton indotineae (T. indotineae), previously known as Trichophyton mentagrophytes genotype VIII, is particularly alarming given that terbinafine is considered the treatment of choice for dermatophyte infections and the limited number of available antimycotics.
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